Detailed information NTG1085899

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACJVG6_RS09535
• Genome accession: NZ_CP177180
• Coordinates: 2008382..2008819 (-)
• Length: 145 a.a.
• NCBI ID: WP_002887014.1
• Uniprot ID: A0A1V0GF29
• Organism: Streptococcus salivarius strain MRD-KRBY
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2003382..2013819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJVG6_RS09500	-	2003425..2004087 (-)	663	WP_002887009.1	CPBP family intramembrane glutamic endopeptidase	-
ACJVG6_RS09505	-	2004200..2004646 (-)	447	WP_037605837.1	hypothetical protein	-
ACJVG6_RS09510	-	2004720..2005376 (-)	657	WP_002887011.1	CPBP family intramembrane glutamic endopeptidase	-
ACJVG6_RS09515	-	2005388..2005585 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
ACJVG6_RS09520	-	2005836..2007029 (-)	1194	WP_002885831.1	acetate kinase	-
ACJVG6_RS09525	comYH	2007086..2008042 (-)	957	WP_002887012.1	class I SAM-dependent methyltransferase	Machinery gene
ACJVG6_RS09530	comGG	2008087..2008404 (-)	318	WP_002887013.1	competence type IV pilus minor pilin ComGG	-
ACJVG6_RS09535	comYF	2008382..2008819 (-)	438	WP_002887014.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACJVG6_RS09540	comGE	2008806..2009036 (-)	231	WP_002887015.1	competence type IV pilus minor pilin ComGE	-
ACJVG6_RS09545	comYD	2009068..2009496 (-)	429	WP_254593949.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACJVG6_RS09550	comYC	2009456..2009770 (-)	315	WP_170314557.1	competence type IV pilus major pilin ComGC	Machinery gene
ACJVG6_RS09555	comYB	2009779..2010879 (-)	1101	WP_139053029.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACJVG6_RS09560	comGA/cglA/cilD	2010761..2011702 (-)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
ACJVG6_RS09565	-	2011781..2012143 (-)	363	WP_002887019.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16155.57 Da
• Isoelectric Point: 8.4658

>NTDB_id=1085899 ACJVG6_RS09535 WP_002887014.1 2008382..2008819(-) (comYF) [Streptococcus salivarius strain MRD-KRBY]
MSLNSKVRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVKQQESQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKASTISQNNQIVTIQVTLKNGLQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1085899 ACJVG6_RS09535 WP_002887014.1 2008382..2008819(-) (comYF) [Streptococcus salivarius strain MRD-KRBY]
ATGTCTCTCAATAGCAAGGTTCGTGCTTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTGATTGCTGGTTCAGTTCA
AGTTTATCAAGGTCTGACCACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAGCCAAGACTGGCTTCTAT
TCGTTCAACAAATGGAGGCAGAATTAGAAGGTTGTCAGTTGGTAAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTAGCTTTTGGACTATCAAGTGCTACTGATTTTCGAAAAACAAATGCTGACGGTCGAGGCTACCAACCCAT
GCTTTTTAATGTAAAAGCTAGTACAATTAGCCAAAATAACCAGATAGTCACCATCCAAGTGACTCTTAAAAATGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

3D structure

• AlphaFold DB: A0A1V0GF29

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae Rx1	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae D39	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae R6	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae TIGR4	50	97.931	0.49
comGF/cglF	Streptococcus mitis SK321	47.222	99.31	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.222	99.31	0.469
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434