Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACJVC4_RS01035 Genome accession   NZ_CP177179
Coordinates   192260..193009 (+) Length   249 a.a.
NCBI ID   WP_037597351.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 187260..198009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS01015 - 188275..189015 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  ACJVC4_RS01020 - 189015..190562 (-) 1548 WP_037597348.1 ABC transporter substrate-binding protein/permease -
  ACJVC4_RS01025 - 190768..191622 (+) 855 WP_002889764.1 undecaprenyl-diphosphate phosphatase -
  ACJVC4_RS01030 - 191682..192053 (-) 372 WP_002889766.1 DUF3021 family protein -
  ACJVC4_RS01035 mecA 192260..193009 (+) 750 WP_037597351.1 adaptor protein MecA Regulator
  ACJVC4_RS01040 - 193013..194170 (+) 1158 WP_002889771.1 glycosyltransferase family 4 protein -
  ACJVC4_RS01045 sufC 194332..195102 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  ACJVC4_RS01050 sufD 195139..196401 (+) 1263 WP_002889773.1 Fe-S cluster assembly protein SufD -
  ACJVC4_RS01055 - 196455..197687 (+) 1233 WP_002889774.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29085.67 Da        Isoelectric Point: 4.0356

>NTDB_id=1085777 ACJVC4_RS01035 WP_037597351.1 192260..193009(+) (mecA) [Streptococcus salivarius strain MRD-NRLLH]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGNVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1085777 ACJVC4_RS01035 WP_037597351.1 192260..193009(+) (mecA) [Streptococcus salivarius strain MRD-NRLLH]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGGGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTACACAAGGCTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GAATGTCTACTATATGACAATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCAAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTGCAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

59.836

97.992

0.586
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment