Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   ACK2I7_RS08515 Genome accession   NZ_CP176632
Coordinates   1724561..1725883 (-) Length   440 a.a.
NCBI ID   WP_021002245.1    Uniprot ID   A0AAP6EML3
Organism   Streptococcus anginosus strain SFAD 40     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719561..1730883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS08495 - 1720888..1723464 (+) 2577 WP_057489850.1 YfhO family protein -
  ACK2I7_RS08510 comE 1723812..1724561 (-) 750 WP_021002244.1 competence system response regulator transcription factor ComE Regulator
  ACK2I7_RS08515 comD/comD2 1724561..1725883 (-) 1323 WP_021002245.1 GHKL domain-containing protein Regulator
  ACK2I7_RS08520 - 1725898..1726047 (-) 150 WP_021002246.1 bacteriocin -
  ACK2I7_RS08530 rlmH 1726329..1726808 (-) 480 WP_041784074.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACK2I7_RS08535 htrA 1727002..1728192 (+) 1191 WP_021002247.1 S1C family serine protease Regulator
  ACK2I7_RS08540 spo0J 1728247..1729014 (+) 768 WP_021002248.1 ParB/RepB/Spo0J family partition protein Regulator
  ACK2I7_RS08545 dnaA 1729243..1730586 (+) 1344 WP_021001132.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51742.42 Da        Isoelectric Point: 7.9865

>NTDB_id=1081739 ACK2I7_RS08515 WP_021002245.1 1724561..1725883(-) (comD/comD2) [Streptococcus anginosus strain SFAD 40]
MNLDKIFIIISFIIGILSFSIVHKKISKVKIIDFRFTLLCLCLFLFSSFINSINSLLAYLCLLLEPVIIYFYFYRFKKYE
KCISVFATFLIYSSVTTSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1081739 ACK2I7_RS08515 WP_021002245.1 1724561..1725883(-) (comD/comD2) [Streptococcus anginosus strain SFAD 40]
ATGAATCTGGATAAAATATTTATAATCATTTCTTTTATTATCGGAATTTTATCTTTTTCAATTGTTCATAAAAAAATTAG
TAAAGTGAAAATTATAGATTTTCGCTTTACTTTATTGTGCTTGTGTTTATTTTTATTTTCATCTTTTATAAATTCGATTA
ATTCCTTATTAGCCTATTTATGTTTATTATTAGAGCCTGTTATAATTTACTTCTATTTTTATCGTTTTAAGAAATATGAG
AAGTGTATATCAGTTTTTGCAACCTTTTTAATTTATTCATCTGTAACTACCTCTGAAACCTTCTTTTCAGTTATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTTTCA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAGAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTATAAT
GAAATTCGAGGCTTTCGGCATGATTATGGCGGAATGTTGGCAAGCTTCCAATCGGCCATTCATACAGGTGATATAAAAGA
AGTAGAACGAATTTATCAGGAGGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTATTTAAGGCACGTGATTACAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAAGCCCTTGCCGATTAAATTGTTAGATCTGGTTAGAATGACAAGCGTCCTTTTGAATAA
TGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TCATTCAAAATTCACGTAAGAAAAGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

55.506

100

0.561
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

59.635

87.273

0.52
  comD/comD1 Streptococcus pneumoniae R6

43.88

98.409

0.432
  comD/comD1 Streptococcus pneumoniae Rx1

43.88

98.409

0.432
  comD/comD1 Streptococcus pneumoniae D39

43.88

98.409

0.432
  comD Streptococcus mitis SK321

44.235

96.591

0.427
  comD Streptococcus mitis NCTC 12261

48.257

84.773

0.409
  comD/comD2 Streptococcus pneumoniae TIGR4

47.453

84.773

0.402

Multiple sequence alignment