Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACK2I7_RS01105 Genome accession   NZ_CP176632
Coordinates   222254..223006 (+) Length   250 a.a.
NCBI ID   WP_021001304.1    Uniprot ID   A0AAP6BPK5
Organism   Streptococcus anginosus strain SFAD 40     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 217254..228006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS01090 csm5 217528..218622 (+) 1095 WP_070836495.1 type III-A CRISPR-associated RAMP protein Csm5 -
  ACK2I7_RS01095 csm6 218619..219776 (+) 1158 WP_084740930.1 type III-A CRISPR-associated CARF protein Csm6 -
  ACK2I7_RS01100 csm6 219786..221066 (+) 1281 WP_084740928.1 type III-A CRISPR-associated CARF protein Csm6 -
  ACK2I7_RS01105 mecA 222254..223006 (+) 753 WP_021001304.1 adaptor protein MecA Regulator
  ACK2I7_RS01110 - 222997..224163 (+) 1167 WP_041783991.1 glycosyltransferase family 4 protein -
  ACK2I7_RS01115 sufC 224256..225026 (+) 771 WP_041783992.1 Fe-S cluster assembly ATPase SufC -
  ACK2I7_RS01120 sufD 225066..226328 (+) 1263 WP_021001307.1 Fe-S cluster assembly protein SufD -
  ACK2I7_RS01125 - 226344..227576 (+) 1233 WP_021001308.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28968.80 Da        Isoelectric Point: 4.1287

>NTDB_id=1081692 ACK2I7_RS01105 WP_021001304.1 222254..223006(+) (mecA) [Streptococcus anginosus strain SFAD 40]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMESEENSDELTQKYIYYIL
KFSSLKEAIVFSKTVDYAVNTSELYKMDDHYYLTILVDIEGRPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNEA
VASLQKVKCL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1081692 ACK2I7_RS01105 WP_021001304.1 222254..223006(+) (mecA) [Streptococcus anginosus strain SFAD 40]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTAGTCCCACAAGAAAAAACAGAAGAGTTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGCGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTCGATGATTTGGCAGATTTGCCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAGTCAGAGGAAAATAGTGACGAACTAACGCAGAAATATATTTATTACATTTTG
AAATTTTCTAGCCTGAAAGAAGCAATTGTTTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAAAAT
GGACGACCACTATTATTTGACAATCTTGGTTGATATTGAAGGGCGTCCAAAGCGTTATCCAGCTTGGCTCCTGGCTTTGA
TGCGTGAGCATGCAGAGGATACGGATGTGACAAGAGCTGTTTTGCAAGAACACGGTTACTTATTGCTTGTCAACGAGGCG
GTTGCCAGTCTTCAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.397

98.8

0.656
  mecA Streptococcus pneumoniae D39

66.397

98.8

0.656
  mecA Streptococcus pneumoniae R6

66.397

98.8

0.656
  mecA Streptococcus pneumoniae TIGR4

65.992

98.8

0.652
  mecA Streptococcus mutans UA159

50.602

99.6

0.504
  mecA Streptococcus thermophilus LMD-9

45.882

100

0.468
  mecA Streptococcus thermophilus LMG 18311

45.49

100

0.464

Multiple sequence alignment