Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACKVMU_RS01340 Genome accession   NZ_CP176094
Coordinates   277088..278392 (-) Length   434 a.a.
NCBI ID   WP_409173722.1    Uniprot ID   -
Organism   Enterococcus mundtii strain Dm     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 272088..283392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKVMU_RS01305 (ACKVMU_01305) - 272513..273472 (-) 960 WP_062805833.1 glycosyltransferase family 2 protein -
  ACKVMU_RS01310 (ACKVMU_01310) - 273611..273961 (-) 351 WP_169058533.1 PepSY domain-containing protein -
  ACKVMU_RS01315 (ACKVMU_01315) pepA 274163..275242 (+) 1080 WP_023518981.1 glutamyl aminopeptidase -
  ACKVMU_RS01320 (ACKVMU_01320) - 275366..275686 (+) 321 WP_019724278.1 thioredoxin family protein -
  ACKVMU_RS01325 (ACKVMU_01325) - 275708..276163 (+) 456 WP_409173720.1 universal stress protein -
  ACKVMU_RS01330 (ACKVMU_01330) - 276215..276436 (+) 222 WP_010736526.1 hypothetical protein -
  ACKVMU_RS01335 (ACKVMU_01335) ytpR 276433..277038 (+) 606 WP_409173721.1 YtpR family tRNA-binding protein -
  ACKVMU_RS01340 (ACKVMU_01340) htrA 277088..278392 (-) 1305 WP_409173722.1 S1C family serine protease Regulator
  ACKVMU_RS01345 (ACKVMU_01345) rlmH 278821..279300 (+) 480 WP_010736523.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACKVMU_RS01350 (ACKVMU_01350) - 279656..280051 (+) 396 WP_409173723.1 hypothetical protein -
  ACKVMU_RS01355 (ACKVMU_01355) - 279981..281288 (+) 1308 WP_349521008.1 hypothetical protein -
  ACKVMU_RS01360 (ACKVMU_01360) - 281285..281881 (+) 597 WP_062805828.1 hypothetical protein -
  ACKVMU_RS01365 (ACKVMU_01365) - 281871..282209 (+) 339 WP_051377614.1 DUF4176 domain-containing protein -
  ACKVMU_RS01370 (ACKVMU_01370) - 282410..283003 (+) 594 WP_409173724.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 45052.00 Da        Isoelectric Point: 4.4838

>NTDB_id=1079664 ACKVMU_RS01340 WP_409173722.1 277088..278392(-) (htrA) [Enterococcus mundtii strain Dm]
MDRKDVTPKMKKRKSNGIWRKLGLGVVGGVIGGLLTFGIFYAATGGGNSVTTSSSSGTQNASGETVVENVKVNVDSDITS
AVDKVQGAVVSVINLQKQSSSSDPFGSLFGQQQESSGEDGELQAYSEGSGVIYKKEGGSAYIVTNNHVVDGQQGLEVLLK
DGTKVKAELVGTDAYTDLAVLKISADKVDTVASFGDSASLKVGEPAIAIGSPLGSQYANSVTSGIISSLNRQVTSTNESN
ETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSDSSSVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMTDLSAVSTQQQEQILKLPSSVTNGVIIRSVQPATPAEKAGLEQYDVITKIDDTEVSSGVELQSVLYGKKVGDTVKIT
YYRGEEEKTVDIKLTIDNTALNQGNSNSSNGSNN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=1079664 ACKVMU_RS01340 WP_409173722.1 277088..278392(-) (htrA) [Enterococcus mundtii strain Dm]
ATGGACAGAAAAGATGTGACACCAAAAATGAAAAAAAGAAAATCTAATGGCATTTGGCGAAAGCTAGGTCTTGGCGTAGT
TGGTGGCGTGATTGGCGGATTACTGACTTTCGGTATTTTTTATGCAGCAACTGGAGGTGGTAACTCAGTAACGACTTCTT
CTAGCAGTGGGACACAAAATGCATCAGGCGAAACAGTTGTCGAAAATGTAAAAGTCAATGTAGATTCAGATATCACTTCT
GCAGTAGATAAAGTACAAGGAGCAGTTGTTTCTGTTATCAACCTACAAAAACAAAGTTCATCATCTGACCCGTTTGGTTC
ATTATTTGGCCAACAACAAGAAAGTAGTGGCGAAGATGGCGAATTGCAAGCTTACAGTGAAGGTAGCGGTGTGATCTATA
AAAAAGAGGGCGGTTCCGCTTATATCGTGACGAATAATCACGTGGTCGATGGACAACAAGGGTTAGAAGTTTTATTAAAA
GATGGAACAAAAGTGAAAGCAGAATTAGTCGGTACAGATGCTTACACTGATTTAGCTGTGTTGAAAATCAGTGCTGACAA
AGTCGACACTGTTGCTTCATTTGGCGATTCTGCTTCATTGAAAGTCGGCGAACCTGCGATTGCGATTGGTTCTCCTCTAG
GTTCTCAATACGCGAATTCCGTAACATCAGGGATCATTTCTTCCTTGAATCGCCAAGTGACAAGTACCAATGAATCTAAT
GAAACGGTCAATATCAACGCGATTCAAACAGATGCAGCGATCAACCCGGGGAACTCTGGTGGTCCACTAGTTAATATCGA
AGGACAAGTCATTGGTATCAATTCAAGTAAAATTGCATCGACTTCTGATTCTTCAAGTGTAAGTGTTGAAGGAATGGGCT
TTGCGATTCCAAGTAATGATGTCGTAAATATCATCAATCAACTTGAAAAAGATGGAAAAGTAACACGCCCTGCACTGGGT
ATCACAATGACCGATCTTTCCGCCGTTTCTACACAACAACAGGAACAGATCTTGAAATTACCATCTTCTGTAACAAATGG
CGTGATCATTCGTTCGGTTCAACCAGCAACGCCTGCGGAAAAAGCTGGCTTAGAACAATATGATGTCATCACAAAAATCG
ATGATACAGAAGTCTCATCTGGTGTTGAATTACAGTCTGTGCTTTATGGTAAAAAAGTTGGTGACACTGTGAAGATCACT
TATTACCGTGGCGAAGAAGAAAAAACTGTAGATATCAAATTGACAATTGATAATACTGCATTAAATCAAGGAAATTCAAA
TAGTTCCAATGGCTCAAATAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(128-273)

PDZ domain (PDZ_2)

(317-414)

Peptidase family M50 (Peptidase_M50)

(12-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.01

90.092

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

51.852

93.318

0.484
  htrA Streptococcus mitis NCTC 12261

52.778

91.244

0.482
  htrA Streptococcus pneumoniae Rx1

58.631

77.419

0.454
  htrA Streptococcus pneumoniae D39

58.631

77.419

0.454
  htrA Streptococcus pneumoniae R6

58.631

77.419

0.454
  htrA Streptococcus pneumoniae TIGR4

58.631

77.419

0.454

Multiple sequence alignment