Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RBL01_RS01150 Genome accession   NZ_CP175675
Coordinates   232704..233993 (-) Length   429 a.a.
NCBI ID   WP_307780895.1    Uniprot ID   -
Organism   Enterococcus sp. SB12     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 227704..238993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RBL01_RS01120 (RBL01_001120) - 228105..229052 (-) 948 WP_002289860.1 glycosyltransferase family 2 protein -
  RBL01_RS01125 (RBL01_001125) - 229275..229625 (-) 351 WP_002289862.1 PepSY domain-containing protein -
  RBL01_RS01130 (RBL01_001130) pepA 229825..230904 (+) 1080 WP_002294156.1 glutamyl aminopeptidase -
  RBL01_RS01135 (RBL01_001135) - 231047..231367 (+) 321 WP_002287837.1 thioredoxin family protein -
  RBL01_RS01140 (RBL01_001140) - 231389..231853 (+) 465 WP_038809452.1 universal stress protein -
  RBL01_RS01145 (RBL01_001145) ytpR 232060..232665 (+) 606 WP_002294153.1 YtpR family tRNA-binding protein -
  RBL01_RS01150 (RBL01_001150) htrA 232704..233993 (-) 1290 WP_307780895.1 S1C family serine protease Regulator
  RBL01_RS01155 (RBL01_001155) rlmH 234422..234901 (+) 480 WP_002287841.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RBL01_RS01160 (RBL01_001160) - 235090..236886 (-) 1797 WP_130624765.1 nuclease domain-containing protein -
  RBL01_RS01165 (RBL01_001165) - 236870..238864 (-) 1995 WP_024636244.1 McrB family protein -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 44893.88 Da        Isoelectric Point: 4.5943

>NTDB_id=1078626 RBL01_RS01150 WP_307780895.1 232704..233993(-) (htrA) [Enterococcus sp. SB12]
MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAMGTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKA
VDKVQDAVVSVINLQSHNQSSGFGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANSVTSGIVSSLNRQVTSTNESNE
TVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMVDLSAVSTQQQEQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKKVGDSVKIT
YYEGSKEKTTTVELTIDQSALKQNQNSEN

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=1078626 RBL01_RS01150 WP_307780895.1 232704..233993(-) (htrA) [Enterococcus sp. SB12]
ATGGATAGAAAAAATGTGACACCAAAGATGAAAAAAAATAAAAATAATAGCCTCTGGCGTAAGTTAGGTCTGGGGCTTGT
TGGAGGGATCGTTGGAGGACTACTGACAGCTGGCATTTTTTATGCAGCGATGGGCACTGGCAACAATAGTTCTACTGCTA
CAAGCGGCAATCAGAATTCTGCCGGTGAAACAGTTGTGGAAAATGTCAAAGTCAATGTAGATTCTGATATCACCAAAGCG
GTAGATAAAGTTCAAGACGCTGTCGTTTCTGTTATCAACTTACAAAGTCATAACCAATCAAGCGGTTTTGGCGGACTATT
CGGGCAGCAAGAAGAAAGTAGCAGCTCAGATGATAGTAATTTGGAAGCTTATAGTGAAGGAAGCGGCGTGATCTACAAAA
AAGACGGGAATACTGCTTATGTAGTCACGAATAATCACGTAGTAGATGGCCAGCAAGGTCTTGAAGTCTTGATGAAAGAC
GGTACGAAGGTAAAAGCTGAATTAGTTGGAACAGATGCTTATTCAGATTTAGCGGTGTTGAAGATCAATTCAGACAAAGT
CGAAACAGTTGCCTCTTTTGGTGACTCAAGTGCTCTGAAGGTTGGTGAGCCTGCGATTGCGATTGGTTCCCCACTAGGAT
CTGAATATGCAAATTCTGTCACTTCAGGAATCGTTTCTTCCTTGAACCGACAAGTGACAAGTACGAATGAATCGAACGAA
ACAGTCAATATCAATGCGATCCAAACAGATGCAGCAATCAACCCTGGAAATTCTGGTGGTCCTTTAGTTAATATCGAAGG
ACAAGTTATCGGTATCAACTCAAGTAAGATCGCAAGTACTTCTGAATCTACTTCTAATGTAAGCGTAGAAGGAATGGGAT
TTGCTATTCCAAGTAACGATGTAGTGAATATCATCAATCAACTGGAAAAAGACGGAAAAGTGACACGTCCAGCTCTAGGT
ATCACAATGGTCGACTTATCTGCCGTTTCTACTCAGCAACAAGAACAAATCTTGAAGATTCCTTCATCTGTAACTAACGG
TGTCATCGTGACAAATGTCCAAACAGCTACACCGGCTGAAAAAGCTGGATTGAAACAATACGACGTCATTACTAAGATCG
ATGACAAAGAAGTTTCTTCTGGTGTAGAACTTCAATCTGCTTTGTATAAGAAAAAAGTGGGAGATTCTGTCAAAATCACT
TACTATGAAGGCTCGAAAGAAAAAACAACTACTGTTGAATTGACGATCGATCAATCGGCATTAAAACAAAATCAAAATAG
TGAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(127-272)

PDZ domain (PDZ_2)

(317-414)

Peptidase family M50 (Peptidase_M50)

(10-417)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.822

91.841

0.503
  htrA Streptococcus mutans UA159

60.169

82.517

0.496
  htrA Streptococcus mitis NCTC 12261

53.03

92.308

0.49
  htrA Streptococcus pneumoniae TIGR4

59.347

78.555

0.466
  htrA Streptococcus pneumoniae D39

59.347

78.555

0.466
  htrA Streptococcus pneumoniae Rx1

59.347

78.555

0.466
  htrA Streptococcus pneumoniae R6

59.347

78.555

0.466

Multiple sequence alignment