Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACI1SY_RS02190 Genome accession   NZ_CP174196
Coordinates   456219..456914 (+) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus petauri strain L9     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 451219..461914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI1SY_RS02165 (ACI1SY_02165) - 451452..452153 (+) 702 WP_019292081.1 DeoR/GlpR family DNA-binding transcription regulator -
  ACI1SY_RS02170 (ACI1SY_02170) pfkB 452150..453076 (+) 927 WP_019292080.1 1-phosphofructokinase -
  ACI1SY_RS02175 (ACI1SY_02175) - 453091..454995 (+) 1905 WP_019292079.1 fructose-specific PTS transporter subunit EIIC -
  ACI1SY_RS02180 (ACI1SY_02180) - 455107..455349 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  ACI1SY_RS02185 (ACI1SY_02185) - 455566..456117 (+) 552 WP_173816776.1 DUF177 domain-containing protein -
  ACI1SY_RS02190 (ACI1SY_02190) covR 456219..456914 (+) 696 WP_019292077.1 response regulator transcription factor Regulator
  ACI1SY_RS02195 (ACI1SY_02195) covS 457002..458492 (+) 1491 WP_173816774.1 HAMP domain-containing histidine kinase Regulator
  ACI1SY_RS02200 (ACI1SY_02200) - 458888..460459 (+) 1572 WP_173816772.1 ABC transporter permease subunit -
  ACI1SY_RS02205 (ACI1SY_02205) - 460460..461197 (+) 738 WP_406813047.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=1074855 ACI1SY_RS02190 WP_019292077.1 456219..456914(+) (covR) [Lactococcus petauri strain L9]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1074855 ACI1SY_RS02190 WP_019292077.1 456219..456914(+) (covR) [Lactococcus petauri strain L9]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACTATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCACACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGCGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGATGTCGTAACACGCGAATACCTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424

Multiple sequence alignment