Detailed information NTG1074856

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: ACI1SY_RS02195
• Genome accession: NZ_CP174196
• Coordinates: 457002..458492 (+)
• Length: 496 a.a.
• NCBI ID: WP_173816774.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain L9
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 452002..463492

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI1SY_RS02170 (ACI1SY_02170)	pfkB	452150..453076 (+)	927	WP_019292080.1	1-phosphofructokinase	-
ACI1SY_RS02175 (ACI1SY_02175)	-	453091..454995 (+)	1905	WP_019292079.1	fructose-specific PTS transporter subunit EIIC	-
ACI1SY_RS02180 (ACI1SY_02180)	-	455107..455349 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
ACI1SY_RS02185 (ACI1SY_02185)	-	455566..456117 (+)	552	WP_173816776.1	DUF177 domain-containing protein	-
ACI1SY_RS02190 (ACI1SY_02190)	covR	456219..456914 (+)	696	WP_019292077.1	response regulator transcription factor	Regulator
ACI1SY_RS02195 (ACI1SY_02195)	covS	457002..458492 (+)	1491	WP_173816774.1	HAMP domain-containing histidine kinase	Regulator
ACI1SY_RS02200 (ACI1SY_02200)	-	458888..460459 (+)	1572	WP_173816772.1	ABC transporter permease subunit	-
ACI1SY_RS02205 (ACI1SY_02205)	-	460460..461197 (+)	738	WP_406813047.1	amino acid ABC transporter ATP-binding protein	-
ACI1SY_RS02210 (ACI1SY_02210)	murD	461337..462698 (+)	1362	WP_019292073.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56960.10 Da
• Isoelectric Point: 5.4181

>NTDB_id=1074856 ACI1SY_RS02195 WP_173816774.1 457002..458492(+) (covS) [Lactococcus petauri strain L9]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQKKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=1074856 ACI1SY_RS02195 WP_173816774.1 457002..458492(+) (covS) [Lactococcus petauri strain L9]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGAAAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGATATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACGACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56