Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACI5FS_RS09010 Genome accession   NZ_CP174003
Coordinates   1783117..1784256 (-) Length   379 a.a.
NCBI ID   WP_406244798.1    Uniprot ID   -
Organism   Leuconostoc mesenteroides strain DMLM17     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1778117..1789256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI5FS_RS08990 (ACI5FS_08990) - 1778493..1779158 (+) 666 WP_010285559.1 NAD(P)H-hydrate epimerase -
  ACI5FS_RS08995 (ACI5FS_08995) - 1779243..1779695 (-) 453 WP_011680485.1 Rrf2 family transcriptional regulator -
  ACI5FS_RS09000 (ACI5FS_09000) - 1779749..1781914 (-) 2166 WP_025268544.1 YhgE/Pip domain-containing protein -
  ACI5FS_RS09005 (ACI5FS_09005) rlmH 1782008..1782487 (-) 480 WP_011680487.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACI5FS_RS09010 (ACI5FS_09010) htrA 1783117..1784256 (-) 1140 WP_406244798.1 S1C family serine protease Regulator
  ACI5FS_RS09015 (ACI5FS_09015) yycI 1784317..1785120 (-) 804 WP_010289058.1 two-component system regulatory protein YycI -
  ACI5FS_RS09020 (ACI5FS_09020) - 1785177..1786469 (-) 1293 WP_025268545.1 hypothetical protein -
  ACI5FS_RS09025 (ACI5FS_09025) walK 1786459..1788324 (-) 1866 WP_025268546.1 cell wall metabolism sensor histidine kinase WalK -
  ACI5FS_RS09030 (ACI5FS_09030) yycF 1788392..1789099 (-) 708 WP_010281559.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39237.50 Da        Isoelectric Point: 9.7777

>NTDB_id=1074031 ACI5FS_RS09010 WP_406244798.1 1783117..1784256(-) (htrA) [Leuconostoc mesenteroides strain DMLM17]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVEATSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTNVEGMGFAIPSDQVVDIVNKLVKDGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKHSLGDTITLTYYHQDTKQTVKVKLTQKLAS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=1074031 ACI5FS_RS09010 WP_406244798.1 1783117..1784256(-) (htrA) [Leuconostoc mesenteroides strain DMLM17]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAGCAGGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTGAGTACGACAGCAACAAGTACAAAAACGATTGCCAAGA
ATGCAACTGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTGAACTTTACTAAATCCAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACGGATGGATCGGCATTTATTGTAACGAATAATCA
CGTAATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCTACATTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAAATCGACGGCACAGACGTTACAACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAATGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGCATCATTTC
GGCCAAGAAAAGGTTAGTTGAGGCAACATCTGAAAATGGTCAAAATTATGGTGGATCCACGGTTATTCAGACGGATGCTG
CTATTAATCCTGGTAACTCAGGTGGACCATTAATCAACTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTATCA
ACATCTTCTTCTGGAACGAACGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAGATGGTAAAGTCACACGACCAGCAATTGGCATTAGTTTGATTAATTTGTCAGAAGTAACAGCTTCTGAGCAAA
AATCAACACTGAAAATTCCAGATAGCGTTACTGGTGGTGTTGTTGTAATGAGTTTGACTAACAATGGCCCAGCAGATAAA
GCTGGATTGAAGAAGTACGACGTTATTGTTGGCATTAATGGTAAAAAGGTCAGCTCACAGGCTGATCTGCGAGAAGAACT
CTACAAGCATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGCAAACCGTCAAGGTTAAATTAA
CACAGAAATTGGCAAGCTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(221-375)

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.113

93.668

0.488
  htrA Streptococcus gordonii str. Challis substr. CH1

48.285

100

0.483
  htrA Streptococcus pneumoniae D39

52.632

90.237

0.475
  htrA Streptococcus pneumoniae TIGR4

52.632

90.237

0.475
  htrA Streptococcus pneumoniae R6

52.632

90.237

0.475
  htrA Streptococcus pneumoniae Rx1

52.632

90.237

0.475
  htrA Streptococcus mutans UA159

52.647

89.71

0.472

Multiple sequence alignment