Detailed information NTG1073685

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACI5FU_RS09575
• Genome accession: NZ_CP173687
• Coordinates: 1893886..1896033 (+)
• Length: 715 a.a.
• NCBI ID: WP_096638837.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides strain DMLM18
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1888886..1901033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI5FU_RS09535 (ACI5FU_09535)	-	1889734..1890459 (+)	726	WP_011679068.1	response regulator transcription factor	-
ACI5FU_RS09540 (ACI5FU_09540)	-	1890731..1890943 (-)	213	WP_405465385.1	hypothetical protein	-
ACI5FU_RS09545 (ACI5FU_09545)	-	1890949..1891122 (-)	174	WP_072612884.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACI5FU_RS09550 (ACI5FU_09550)	-	1891136..1891315 (-)	180	WP_135400366.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACI5FU_RS09555 (ACI5FU_09555)	-	1891937..1892098 (-)	162	WP_080732741.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACI5FU_RS09560 (ACI5FU_09560)	-	1892128..1892268 (-)	141	WP_135400364.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACI5FU_RS09565 (ACI5FU_09565)	-	1892840..1893004 (-)	165	WP_135400363.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACI5FU_RS09570 (ACI5FU_09570)	-	1892997..1893197 (-)	201	WP_036089375.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ACI5FU_RS09575 (ACI5FU_09575)	comA	1893886..1896033 (+)	2148	WP_096638837.1	peptide cleavage/export ABC transporter	Regulator
ACI5FU_RS09580 (ACI5FU_09580)	-	1896036..1897400 (+)	1365	WP_405465389.1	bacteriocin secretion accessory protein	-
ACI5FU_RS09585 (ACI5FU_09585)	-	1898216..1898341 (-)	126	WP_011679061.1	putative metal homeostasis protein	-
ACI5FU_RS09590 (ACI5FU_09590)	-	1898457..1899194 (-)	738	WP_002815471.1	SDR family NAD(P)-dependent oxidoreductase	-
ACI5FU_RS09595 (ACI5FU_09595)	-	1899252..1899593 (-)	342	WP_240742627.1	hypothetical protein	-
ACI5FU_RS09600 (ACI5FU_09600)	-	1899690..1899839 (-)	150	WP_240742626.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80350.34 Da
• Isoelectric Point: 9.2370

>NTDB_id=1073685 ACI5FU_RS09575 WP_096638837.1 1893886..1896033(+) (comA) [Leuconostoc mesenteroides strain DMLM18]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFNMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDAYIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=1073685 ACI5FU_RS09575 WP_096638837.1 1893886..1896033(+) (comA) [Leuconostoc mesenteroides strain DMLM18]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACGCTGTCAAACATCCCTATCGGGTACAACGGCGCTAGGCTTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCAACATGAAAGATTTGCCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATGCTTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAATTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTCACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGCAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTGCTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGTGCTCGTGAAAATACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.944	99.86	0.599
comA	Streptococcus mitis NCTC 12261	58.146	99.58	0.579
comA	Streptococcus mitis SK321	57.865	99.58	0.576
comA	Streptococcus pneumoniae Rx1	57.584	99.58	0.573
comA	Streptococcus pneumoniae D39	57.584	99.58	0.573
comA	Streptococcus pneumoniae R6	57.584	99.58	0.573
comA	Streptococcus pneumoniae TIGR4	57.303	99.58	0.571
comA/nlmT	Streptococcus mutans UA159	54.29	99.441	0.54