Detailed information NTG0107346

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ACAM22_RS08215
• Genome accession: NZ_AP028929
• Coordinates: 1789932..1790999 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159550.1
• Uniprot ID: F9HAA0
• Organism: Streptococcus sp. SN-1
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1784932..1795999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS08195 (MASAN616_15920)	-	1785845..1786648 (-)	804	WP_369606671.1	ABC transporter ATP-binding protein	-
ACAM22_RS08200 (MASAN616_15930)	-	1786661..1787554 (-)	894	WP_125422242.1	ABC transporter permease	-
ACAM22_RS08205 (MASAN616_15940)	-	1787566..1788543 (-)	978	WP_000869838.1	ABC transporter substrate-binding protein	-
ACAM22_RS08210 (MASAN616_15950)	amiF	1788995..1789921 (-)	927	WP_070842265.1	ATP-binding cassette domain-containing protein	Regulator
ACAM22_RS08215 (MASAN616_15960)	amiE	1789932..1790999 (-)	1068	WP_000159550.1	ABC transporter ATP-binding protein	Regulator
ACAM22_RS08220 (MASAN616_15970)	amiD	1791008..1791934 (-)	927	WP_000103691.1	oligopeptide ABC transporter permease OppC	Regulator
ACAM22_RS08225 (MASAN616_15980)	amiC	1791934..1793430 (-)	1497	WP_000759914.1	ABC transporter permease	Regulator
ACAM22_RS08230 (MASAN616_15990)	amiA3	1793497..1795485 (-)	1989	WP_369606672.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39491.07 Da
• Isoelectric Point: 4.8078

>NTDB_id=107346 ACAM22_RS08215 WP_000159550.1 1789932..1790999(-) (amiE) [Streptococcus sp. SN-1]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFDEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=107346 ACAM22_RS08215 WP_000159550.1 1789932..1790999(-) (amiE) [Streptococcus sp. SN-1]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGAAAATCTGTTT
TGACAAAGACTTTCACAGGTATGCTTGAAGAAAATGGTCGTATTGCTCAAGGAAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAAGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACGATCTTCCAAGACCCGATGACTAG
TTTGGACCCAATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCAA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGGATTCCAGATGCAGATAGACGTTTTGATGAATACCCCTTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATTTGTGACGAGCCAAC
GACTGCCTTGGATGTAACCATCCAAGCACAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTACCATTTCACAACAA
TCTTTATCACCCATGACCTTGGTGTGGTAGCAAGTATTGCGGATAAGGTAGCAGTGATGTATGCAGGAGAAATCGTTGAG
TATGGAACTGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTATGCAATGCAGATTGACTTCGAACAAAAAGCCCCTCAATTCTCAGTATCAGAGACGCATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCACGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCAGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9HAA0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538