Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACAM22_RS07970 Genome accession   NZ_AP028929
Coordinates   1746809..1747546 (-) Length   245 a.a.
NCBI ID   WP_261029340.1    Uniprot ID   A0AAT9G2J1
Organism   Streptococcus sp. SN-1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1741809..1752546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS07945 (MASAN616_15400) blpZ 1742299..1742547 (-) 249 WP_049502002.1 immunity protein BlpZ -
  ACAM22_RS07950 (MASAN616_15420) - 1743153..1743557 (-) 405 WP_369606655.1 immunity protein -
  ACAM22_RS07955 - 1744000..1744119 (-) 120 WP_142760972.1 PncF family bacteriocin immunity protein -
  ACAM22_RS07960 - 1744411..1744767 (-) 357 WP_078237973.1 hypothetical protein -
  ACAM22_RS07965 (MASAN616_15460) - 1745455..1746795 (-) 1341 WP_369606656.1 sensor histidine kinase -
  ACAM22_RS07970 (MASAN616_15470) comE/blpR 1746809..1747546 (-) 738 WP_261029340.1 response regulator transcription factor Regulator
  ACAM22_RS07975 (MASAN616_15480) - 1747551..1747889 (-) 339 WP_153199232.1 LytTR family DNA-binding domain-containing protein -
  ACAM22_RS07980 (MASAN616_15490) - 1748272..1748601 (+) 330 WP_084861873.1 helicase BlpT -
  ACAM22_RS07985 (MASAN616_15500) pptB 1748663..1749712 (-) 1050 WP_369606657.1 ABC transporter permease Regulator
  ACAM22_RS07990 (MASAN616_15510) pptA 1749709..1750440 (-) 732 WP_369606658.1 ABC transporter ATP-binding protein Regulator
  ACAM22_RS07995 (MASAN616_15520) - 1750508..1750918 (+) 411 WP_001278317.1 HIT family protein -
  ACAM22_RS08000 (MASAN616_15530) - 1750928..1751215 (+) 288 WP_084928138.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28749.88 Da        Isoelectric Point: 6.3427

>NTDB_id=107342 ACAM22_RS07970 WP_261029340.1 1746809..1747546(-) (comE/blpR) [Streptococcus sp. SN-1]
MRIFVLEDDFSQQARIETTIEKLLKEHHITPSSFEIFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLHCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=107342 ACAM22_RS07970 WP_261029340.1 1746809..1747546(-) (comE/blpR) [Streptococcus sp. SN-1]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGGCTAGAATTGAAACGACCATTGAGAAACTTTTGAAAGAACA
TCATATCACTCCCAGCTCTTTTGAGATCTTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCGCATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAGGGTCTAGAGGTGGCTAGAAAGATTCGGGATCGAGAC
CCCTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTACATTGATAAGGCTCTTTCAGCAGAGGAGTTTGAATCTCGGATCGAAACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCTGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTTGAAACGTCGCCTAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACGGCGAGTTTAGAGGA
GGTTTTTAAGCAGGAACCCCGTCTCTTGCATTGCCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATCAATAACTTACACTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.846

100

0.543
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment