Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACAM22_RS03330 Genome accession   NZ_AP028929
Coordinates   762605..763342 (+) Length   245 a.a.
NCBI ID   WP_049550643.1    Uniprot ID   A0AAT9G013
Organism   Streptococcus sp. SN-1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 757605..768342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS03310 (MASAN616_06470) - 758585..758770 (+) 186 WP_060805305.1 hypothetical protein -
  ACAM22_RS03315 (MASAN616_06480) - 758772..760199 (+) 1428 WP_261052162.1 cytosine permease -
  ACAM22_RS03320 (MASAN616_06490) - 760332..760889 (-) 558 WP_261052166.1 transposase -
  ACAM22_RS03325 (MASAN616_06500) - 761003..762484 (-) 1482 WP_261052172.1 oligosaccharide flippase family protein -
  ACAM22_RS03330 (MASAN616_06510) mecA 762605..763342 (+) 738 WP_049550643.1 adaptor protein MecA Regulator
  ACAM22_RS03335 (MASAN616_06520) - 763495..764781 (+) 1287 WP_369606946.1 homoserine dehydrogenase -
  ACAM22_RS03340 (MASAN616_06530) thrB 764783..765652 (+) 870 WP_369606947.1 homoserine kinase -
  ACAM22_RS03345 (MASAN616_06540) msrB 765752..766690 (+) 939 WP_369606948.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28526.30 Da        Isoelectric Point: 4.0236

>NTDB_id=107322 ACAM22_RS03330 WP_049550643.1 762605..763342(+) (mecA) [Streptococcus sp. SN-1]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSISEKTKDDIEAIQSLEQVEAREEEQEQAEQEVESKKEPYIYYILSFS
KLADLVAFSKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVIN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=107322 ACAM22_RS03330 WP_049550643.1 762605..763342(+) (mecA) [Streptococcus sp. SN-1]
ATGAAAATGAAACAAATTAGTGATACAACTTTGAAAATTACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACGGAAGAATTCTTTTATGCTATCTTGGATGAGTTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGTTTCCGTGTAACTCCAAAACCTGATAAGGTCGATGTCTTTGTAACCAAATCAAAGATT
GATCAAAATCTAGATTTTGAAGACTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCTGATGAGTTTAT
TAAAACCTTAGAAAAAAGCATCTCAGAAAAGACTAAGGATGATATCGAAGCGATTCAATCTCTAGAGCAAGTCGAAGCCA
GGGAAGAAGAGCAGGAGCAGGCTGAACAAGAAGTTGAAAGCAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTTCT
AAGTTAGCTGATTTGGTGGCTTTTTCAAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTGTTGGCTCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGTTCAGTCTTACAAGAGTATGGCCAAGTCTTGATGAATCACGATGCAGTGATCAAT
CTGCAAAAGATTGGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

96.327

100

0.963
  mecA Streptococcus pneumoniae D39

96.327

100

0.963
  mecA Streptococcus pneumoniae R6

96.327

100

0.963
  mecA Streptococcus pneumoniae TIGR4

95.918

100

0.959
  mecA Streptococcus mutans UA159

48.571

100

0.486
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.185

100

0.469

Multiple sequence alignment