Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACAM22_RS02240 Genome accession   NZ_AP028929
Coordinates   507049..508950 (+) Length   633 a.a.
NCBI ID   WP_369606884.1    Uniprot ID   A0AAT9FZD2
Organism   Streptococcus sp. SN-1     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 502049..513950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS02225 (MASAN616_04300) fmt 504056..504991 (+) 936 WP_101784412.1 methionyl-tRNA formyltransferase -
  ACAM22_RS02230 (MASAN616_04310) rsmB 504984..506297 (+) 1314 WP_369606883.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACAM22_RS02235 (MASAN616_04320) - 506312..507052 (+) 741 WP_153192268.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACAM22_RS02240 (MASAN616_04330) stkP 507049..508950 (+) 1902 WP_369606884.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACAM22_RS02245 (MASAN616_04340) - 509039..509797 (+) 759 WP_261050523.1 threonine/serine exporter family protein -
  ACAM22_RS02250 (MASAN616_04350) - 509799..510248 (+) 450 WP_049550918.1 threonine/serine exporter family protein -
  ACAM22_RS02255 (MASAN616_04360) - 510362..511534 (+) 1173 WP_261050584.1 hydroxymethylglutaryl-CoA synthase -
  ACAM22_RS02260 (MASAN616_04370) - 511534..512808 (+) 1275 WP_261050521.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69031.40 Da        Isoelectric Point: 9.3842

>NTDB_id=107317 ACAM22_RS02240 WP_369606884.1 507049..508950(+) (stkP) [Streptococcus sp. SN-1]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYNRRNEPKLVFNDTTKADTKTLPKVSQSTLTSIPKVQTQSPKPQAA
KPSQQVSEDDYATKPVKKRKFRVRYMILLASIVLVAASLVWILSRTPATIAIPNVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPDAGTGRKEGTKINLVVSSGKQSFQLSNYIGRKSTDVIAELKQKKVPENLIKIEEEESSESEAGTV
LRQSPAAGTTYDLSKVSTITLTVAKKVTSVAMPSYTGSSLEFTKNNLVQIVGIKEANIEVVEVSTAPAGTAEGTVVEQSP
KAGEKVDLTKTRVKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRENAPANTQSSSEGNHENSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=107317 ACAM22_RS02240 WP_369606884.1 507049..508950(+) (stkP) [Streptococcus sp. SN-1]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTGAAACAGATTGGCCGAGGAGGCATGGCGGATGTCTA
TTTGGCCAAGGATTTAATTCTAGACGGAGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACACTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATTATGGGACAAATTCTCTTGGCTATGCGTTTGGCCCATACTAGAGGAATTGTCC
ATAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGCCTTACTCAGACAAACTCAATGTTGGGGTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAGGCGACTGTACAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGCCATATCCCTTATGACG
GGGATAGTGCGGTGACCATCGCCCTTCAGCATTTCCAGAAACCACTGCCGTCAGTTATAGCTGAAAATCCATCTGTGCCT
CAGGCTTTGGAGAATGTTGTCATCAAGGCAACTGCCAAGAAATTGACAGATCGTTATCAGTCAGTTGCAGAGATGTATGT
AGACTTGTCTAGTAGCTTGTCTTACAATCGTCGCAATGAGCCTAAACTGGTATTTAATGATACTACTAAGGCAGACACCA
AGACTCTACCAAAGGTATCCCAGAGTACTCTGACCTCGATTCCTAAGGTACAAACACAAAGTCCGAAGCCACAGGCTGCG
AAGCCGAGTCAGCAGGTTTCAGAAGACGATTACGCAACCAAGCCTGTTAAGAAACGGAAATTTAGAGTTCGCTATATGAT
TTTGTTGGCCAGCATTGTATTGGTAGCAGCTTCTCTTGTTTGGATACTATCCAGAACTCCTGCAACCATTGCTATTCCAA
ATGTGGCAGGTCAGACAGTTGCGGAGGCCAAGGAAACTCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATTCGTACAGATCCTGACGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAATTGAGTAACTATATCGGCCGTAAATCGACAGATGTTATCGCAG
AACTCAAGCAGAAGAAGGTTCCTGAAAATCTCATCAAGATCGAGGAAGAAGAATCAAGTGAGAGTGAAGCAGGAACTGTT
CTCAGACAGAGTCCAGCTGCCGGTACAACCTATGATTTAAGCAAGGTATCAACGATTACCTTAACCGTTGCTAAGAAAGT
AACCAGCGTTGCCATGCCAAGTTATACAGGATCTAGTCTTGAATTTACTAAAAACAATCTCGTTCAAATTGTCGGTATTA
AAGAAGCCAATATTGAAGTTGTAGAAGTGTCGACAGCTCCCGCTGGAACTGCTGAAGGTACAGTCGTTGAACAGAGTCCA
AAAGCAGGTGAAAAGGTTGATTTGACTAAGACGCGTGTCAAGATTTCAATCTACAAGCCAAAAACACCGCCGTCAACGTC
ATCATCGGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACAACACCAAGTCAGGGGAACCAACAAGGAAATCAACGAG
AGAATGCACCTGCTAATACTCAATCAAGTAGTGAAGGCAACCACGAAAATTCACGTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

80.717

92.575

0.747
  stkP Streptococcus pneumoniae D39

80.375

92.575

0.744
  stkP Streptococcus pneumoniae R6

80.375

92.575

0.744
  stkP Streptococcus pneumoniae Rx1

80.205

92.575

0.742
  pknB Streptococcus mutans UA159

55.155

91.943

0.507
  stkP/pknB Streptococcus salivarius strain HSISS4

54.53

92.417

0.504

Multiple sequence alignment