Detailed information NTG1070799

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: ACIVIR_RS02380
• Genome accession: NZ_CP173225
• Coordinates: 435088..436437 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801629.1
• Uniprot ID: A0A0T8X0V4
• Organism: Streptococcus pneumoniae strain 262
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 430088..441437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIVIR_RS02360	blpU	430563..430793 (+)	231	WP_001093487.1	bacteriocin-like peptide BlpU	-
ACIVIR_RS02365	-	430796..430921 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
ACIVIR_RS02370	-	431171..432488 (-)	1318	Protein_418	ISL3 family transposase	-
ACIVIR_RS02375	comA	432922..435075 (+)	2154	WP_050221223.1	peptide cleavage/export ABC transporter ComA	Regulator
ACIVIR_RS02380	comB	435088..436437 (+)	1350	WP_000801629.1	competence pheromone export protein ComB	Regulator
ACIVIR_RS02385	purC	436607..437314 (+)	708	WP_000043313.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ACIVIR_RS02390	-	437325..437459 (+)	135	WP_000429436.1	hypothetical protein	-
ACIVIR_RS02395	-	437516..441241 (+)	3726	WP_114880802.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49525.39 Da
• Isoelectric Point: 5.5618

>NTDB_id=1070799 ACIVIR_RS02380 WP_000801629.1 435088..436437(+) (comB) [Streptococcus pneumoniae strain 262]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGTLLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=1070799 ACIVIR_RS02380 WP_000801629.1 435088..436437(+) (comB) [Streptococcus pneumoniae strain 262]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGGAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTACCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0T8X0V4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae Rx1	99.332	100	0.993
comB	Streptococcus pneumoniae D39	99.332	100	0.993
comB	Streptococcus pneumoniae R6	99.332	100	0.993
comB	Streptococcus pneumoniae TIGR4	99.109	100	0.991
comB	Streptococcus mitis SK321	95.1	100	0.951
comB	Streptococcus mitis NCTC 12261	94.209	100	0.942
comB	Streptococcus gordonii str. Challis substr. CH1	55.778	100	0.559