Detailed information NTG1067826

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACH9ZK_RS11675
• Genome accession: NZ_CP172438
• Coordinates: 2467369..2469561 (-)
• Length: 730 a.a.
• NCBI ID: WP_016388369.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain E11.5
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2462369..2474561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH9ZK_RS11645 (ACH9ZK_11645)	-	2462534..2462818 (-)	285	WP_003580845.1	bacteriocin immunity protein	-
ACH9ZK_RS11650 (ACH9ZK_11650)	-	2463012..2463308 (-)	297	WP_003588783.1	bacteriocin immunity protein	-
ACH9ZK_RS11655 (ACH9ZK_11655)	-	2463410..2464765 (-)	1356	WP_003567335.1	threonine/serine ThrE exporter family protein	-
ACH9ZK_RS11660 (ACH9ZK_11660)	-	2465071..2465382 (-)	312	WP_003580849.1	hypothetical protein	-
ACH9ZK_RS11665 (ACH9ZK_11665)	-	2465455..2465805 (-)	351	WP_003567340.1	hypothetical protein	-
ACH9ZK_RS11670 (ACH9ZK_11670)	-	2465979..2467358 (-)	1380	WP_003596059.1	bacteriocin secretion accessory protein	-
ACH9ZK_RS11675 (ACH9ZK_11675)	comA	2467369..2469561 (-)	2193	WP_016388369.1	peptide cleavage/export ABC transporter	Regulator
ACH9ZK_RS11680 (ACH9ZK_11680)	-	2470027..2470167 (-)	141	WP_016384130.1	bacteriocin-like peptide, LSEI_2386 family	-
ACH9ZK_RS11685 (ACH9ZK_11685)	-	2470358..2471656 (+)	1299	WP_400263685.1	GHKL domain-containing protein	-
ACH9ZK_RS11690 (ACH9ZK_11690)	-	2471661..2472467 (+)	807	WP_003567351.1	LytR/AlgR family response regulator transcription factor	-
ACH9ZK_RS11695 (ACH9ZK_11695)	-	2472829..2473026 (-)	198	WP_016388366.1	hypothetical protein	-
ACH9ZK_RS11700 (ACH9ZK_11700)	-	2473573..2473812 (+)	240	WP_003605974.1	hypothetical protein	-
ACH9ZK_RS11705 (ACH9ZK_11705)	-	2474072..2474245 (-)	174	WP_032675994.1	bacteriocin	-
ACH9ZK_RS11710 (ACH9ZK_11710)	-	2474280..2474468 (-)	189	WP_003567358.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81305.54 Da
• Isoelectric Point: 7.0666

>NTDB_id=1067826 ACH9ZK_RS11675 WP_016388369.1 2467369..2469561(-) (comA) [Lacticaseibacillus paracasei strain E11.5]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=1067826 ACH9ZK_RS11675 WP_016388369.1 2467369..2469561(-) (comA) [Lacticaseibacillus paracasei strain E11.5]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTCATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCTATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTAGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGACTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAGCAAATCAATCTTGAAATCCCAGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCAATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	59.053	98.356	0.581
comA	Streptococcus pneumoniae Rx1	58.496	98.356	0.575
comA	Streptococcus pneumoniae D39	58.496	98.356	0.575
comA	Streptococcus pneumoniae R6	58.496	98.356	0.575
comA	Streptococcus mitis SK321	58.357	98.356	0.574
comA	Streptococcus pneumoniae TIGR4	58.078	98.356	0.571
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	98.356	0.562
comA/nlmT	Streptococcus mutans UA159	54.986	98.904	0.544