Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   ACFSN5_RS08860 Genome accession   NZ_CP172427
Coordinates   1925586..1927445 (-) Length   619 a.a.
NCBI ID   WP_165213381.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1920586..1932445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS08840 (ACFSN5_08840) - 1921781..1922449 (-) 669 WP_165213373.1 fructose-6-phosphate aldolase -
  ACFSN5_RS08845 (ACFSN5_08845) - 1923021..1923671 (-) 651 WP_206221368.1 response regulator transcription factor -
  ACFSN5_RS08850 (ACFSN5_08850) - 1923649..1924686 (-) 1038 WP_165213377.1 sensor histidine kinase -
  ACFSN5_RS08855 (ACFSN5_08855) liaF 1924683..1925381 (-) 699 WP_165213379.1 cell wall-active antibiotics response protein LiaF -
  ACFSN5_RS08860 (ACFSN5_08860) pknB 1925586..1927445 (-) 1860 WP_165213381.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACFSN5_RS08865 (ACFSN5_08865) - 1927442..1928185 (-) 744 WP_165213383.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACFSN5_RS08870 (ACFSN5_08870) rsmB 1928210..1929535 (-) 1326 WP_165213403.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACFSN5_RS08875 (ACFSN5_08875) fmt 1929519..1930460 (-) 942 WP_165213385.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 619 a.a.        Molecular weight: 66932.20 Da        Isoelectric Point: 5.4513

>NTDB_id=1067685 ACFSN5_RS08860 WP_165213381.1 1925586..1927445(-) (pknB) [Streptococcus sp. ZJ 1593]
MIQIGKLFAGRYRILKSVGRGGMADVYLANDLILEGEEVAIKVLRTNYQTDQVAVTRFQREARAMAELSHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKHYIQDKAPLSNSEVVRIMEEVLSAMTLAHEKGIIHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIREINPDVP
QALENVVIKATAKRLNDRYKSTYEMSRDLMSSLSYNRSREAKLVFSDVADTKTLPKIDTNTANASTEQLLKATDKKVKAP
VKPAPKPNEKVKPKRKHKSYSIFSKVAIALVLVLVAIFAFLMLRNPSTVSVPDISGQELSAARTTIKDSGLKVGQVIKVE
SDSVEKGKVVRTDPAAGTSKKEGTSVDIYVSSSGGSFKMKDYTGENSDDAVEDLTSNYGVDKSKIEVTEVSTTDYEEGTI
ISQSPSKGDKFNPSGDDTIKFTVAVSGSTTMPNLTGMTYSQAVSTLTAIGIKSSRIKIYSSSTGSETSPSSSSIISGQNP
YYGASLDLSSNDDIILYVQDASSSSSKSSSLNSTSDEGDSSSDSTTSSSSDDSEPSQSQ

Nucleotide


Download         Length: 1860 bp        

>NTDB_id=1067685 ACFSN5_RS08860 WP_165213381.1 1925586..1927445(-) (pknB) [Streptococcus sp. ZJ 1593]
ATGATCCAGATTGGCAAATTATTTGCTGGTCGCTATCGCATTCTCAAGTCCGTCGGTCGAGGTGGTATGGCTGATGTTTA
CTTGGCTAATGACCTGATTTTGGAAGGAGAAGAGGTTGCCATCAAGGTGCTTCGGACCAACTATCAGACTGACCAAGTAG
CTGTGACACGTTTTCAGCGAGAAGCGCGTGCCATGGCTGAACTCAGCCATCCTAACATTGTTTCAATTAGAGACATTGGC
GAAGAAGATGGGCAGCAGTTCCTTGTAATGGAATATGTTGATGGCTCAGACCTCAAACATTATATTCAGGATAAGGCTCC
CTTATCTAATTCTGAAGTTGTCAGGATTATGGAAGAAGTCCTATCGGCCATGACTTTGGCTCATGAAAAAGGAATCATTC
ACCGTGATCTGAAACCTCAGAATATTCTTTTAACTAAGGATGGCACGGTCAAGGTGACCGACTTTGGAATTGCTGTGGCT
TTTGCGGAGACTAGCTTAACCCAGACAAATTCCATGCTGGGCAGTGTCCATTATCTGTCACCTGAACAGGCACGTGGTTC
TAAAGCAACGGTGCAATCAGACATCTATGCCATGGGGATTATGCTCTTTGAAATGCTGACTGGGCATATTCCTTATGATG
GTGATAGTGCTGTGACCATTGCTCTGCAGCATTTCCAAAAGCCGTTACCATCAATTAGGGAGATTAATCCTGACGTTCCT
CAAGCGCTGGAAAATGTTGTTATTAAGGCAACAGCCAAGCGTTTGAATGATCGCTACAAATCAACCTATGAAATGAGCCG
AGACCTCATGTCCAGTCTCAGCTATAACCGCAGTCGAGAAGCTAAGCTTGTCTTTTCTGATGTGGCGGATACTAAAACCT
TACCGAAAATTGATACCAATACAGCCAATGCTTCGACAGAGCAGCTGCTCAAGGCAACTGATAAAAAGGTTAAAGCACCG
GTAAAACCTGCGCCCAAGCCTAATGAAAAGGTTAAGCCCAAGCGTAAGCATAAGAGCTATAGTATTTTTAGCAAGGTTGC
AATTGCCTTAGTTCTAGTTCTAGTCGCTATTTTTGCTTTTCTGATGCTGCGGAATCCATCGACAGTGTCTGTTCCTGATA
TATCTGGTCAGGAACTGTCGGCTGCGAGGACTACAATTAAAGATTCAGGTCTTAAGGTAGGCCAAGTTATTAAGGTGGAA
AGCGATTCTGTGGAAAAAGGAAAGGTTGTTCGAACTGACCCAGCTGCTGGGACCTCAAAAAAAGAGGGAACATCTGTTGA
TATCTATGTGTCCAGCAGTGGCGGTAGTTTCAAAATGAAGGACTATACGGGGGAAAATTCTGACGATGCTGTAGAAGATC
TGACATCTAATTATGGTGTCGATAAATCAAAAATAGAAGTTACGGAAGTTTCTACGACTGATTATGAAGAAGGAACCATT
ATCAGTCAGAGCCCATCAAAGGGAGATAAATTTAATCCATCTGGTGATGATACCATTAAGTTTACAGTTGCTGTCTCTGG
TTCGACAACGATGCCGAATTTGACAGGTATGACCTACTCTCAGGCTGTATCCACGCTAACAGCGATTGGTATTAAGTCAT
CACGAATTAAGATTTATTCTTCATCGACTGGATCTGAGACTTCGCCATCATCTTCCAGCATTATTTCTGGTCAAAATCCT
TACTATGGAGCCAGCCTAGACCTGTCTTCCAATGATGATATCATCCTCTATGTGCAGGATGCTTCATCGAGCTCATCAAA
GTCAAGCTCATTAAATTCCACAAGCGATGAAGGAGATAGTTCAAGTGATAGTACGACTTCATCCAGTTCGGATGATTCGG
AACCCTCGCAATCACAGTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(438-504)

Protein kinase domain (Pkinase)

(12-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

69.88

93.861

0.656
  stkP/pknB Streptococcus salivarius strain HSISS4

64.915

95.315

0.619
  stkP Streptococcus pneumoniae TIGR4

52.931

96.446

0.51
  stkP Streptococcus pneumoniae D39

52.596

96.446

0.507
  stkP Streptococcus pneumoniae R6

52.596

96.446

0.507
  stkP Streptococcus pneumoniae Rx1

52.429

96.446

0.506

Multiple sequence alignment