Detailed information NTG1067670

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACFSN5_RS04225
• Genome accession: NZ_CP172427
• Coordinates: 915668..917815 (-)
• Length: 715 a.a.
• NCBI ID: WP_165212824.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZJ 1593
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 910668..922815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFSN5_RS04200 (ACFSN5_04200)	-	910942..911802 (+)	861	WP_165212820.1	patatin family protein	-
ACFSN5_RS04205 (ACFSN5_04205)	-	911961..912464 (+)	504	WP_165212855.1	phosphatase PAP2 family protein	-
ACFSN5_RS04210 (ACFSN5_04210)	-	912585..913328 (+)	744	WP_165212821.1	response regulator transcription factor	-
ACFSN5_RS04215 (ACFSN5_04215)	-	913331..914659 (+)	1329	WP_165212822.1	sensor histidine kinase	-
ACFSN5_RS04220 (ACFSN5_04220)	-	914712..915485 (-)	774	WP_165212823.1	HlyD family efflux transporter periplasmic adaptor subunit	-
ACFSN5_RS04225 (ACFSN5_04225)	comA/nlmT	915668..917815 (-)	2148	WP_165212824.1	peptide cleavage/export ABC transporter	Regulator
ACFSN5_RS04230 (ACFSN5_04230)	-	918440..918508 (+)	69	Protein_798	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ACFSN5_RS04235 (ACFSN5_04235)	-	918591..918728 (+)	138	WP_165212827.1	bacteriocin	-
ACFSN5_RS04240 (ACFSN5_04240)	-	918743..918892 (+)	150	WP_165212829.1	hypothetical protein	-
ACFSN5_RS04245 (ACFSN5_04245)	-	918919..919080 (+)	162	WP_165212831.1	hypothetical protein	-
ACFSN5_RS04250 (ACFSN5_04250)	-	919192..919344 (+)	153	WP_165212833.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACFSN5_RS04255 (ACFSN5_04255)	-	919432..919833 (+)	402	WP_165329413.1	hypothetical protein	-
ACFSN5_RS04260 (ACFSN5_04260)	-	920095..920394 (+)	300	WP_165329412.1	bacteriocin immunity protein	-
ACFSN5_RS04265 (ACFSN5_04265)	-	921218..922213 (+)	996	WP_165212839.1	thioredoxin family protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80510.58 Da
• Isoelectric Point: 8.6469

>NTDB_id=1067670 ACFSN5_RS04225 WP_165212824.1 915668..917815(-) (comA/nlmT) [Streptococcus sp. ZJ 1593]
MNFYKFIPQIDARDCGIAALASVARYYGSNYSLAHLRELAKTDKEGTTALGIVEAAKAIGFETQAVRADMSLFDEKDIPF
PFIVHVNKEGKLQHYYVVYKAKKNHFIIGDPDPTVKVTKMKKETFEKEWDGVSIFLAPEPAYKPHKDRKNGLLNFIPLIL
KQKGLIFQISLASLLVTLIDILGSYYLQGILDNYIPNQMLSTLTIVSVGLVITYIIQQIMAFSRDYLLTVLSQRLSIDVI
LAYIRHIFSLPMSFFATRRTGEITSRFSDANAIIDALASTILSIFLDCFILIIIGAVLFLQNTNLFLLTLLSIPIYTVII
FAFMKPFEKMNQEVMEANSMVSSAIIEDINGMETIKSLTSEDTRYRNVDNEFVDYLDKSFNRHKYEVLQTALKKAAQLIL
NVTILWFGSKLVMSNRISIGQLIAYNSLLTYFTNPLENIINLQTKLQSAKVANNRLNEVYLVSSEFDKKTTKVDHSALDG
KIAFSDVSYKYGFGRDTLTDINLTINRGSKISLVGISGSGKTTLAKLIVNFFQPYKGEITINGLNTNLLDKKLLRRYINY
LPQQPYIFSGSILDNLTLGADESVSQEDIMKACELAEIRRDIEQMPLGYQTELSDGAGLSGGQKQRIALARALLTKSPIM
VLDEATSGLDVLTEKKVIDNLMQMTEKTIIFVAHRLSISERTDKIVVLDQGKIIESGSHQDLLKKQGFYYQLFNK

Nucleotide

• Length: 2148 bp

>NTDB_id=1067670 ACFSN5_RS04225 WP_165212824.1 915668..917815(-) (comA/nlmT) [Streptococcus sp. ZJ 1593]
ATGAACTTTTACAAATTTATTCCCCAGATTGATGCTAGAGATTGCGGAATAGCTGCTCTGGCATCCGTTGCCAGATATTA
TGGCTCTAACTATTCCTTAGCGCACTTGCGAGAACTGGCTAAGACCGATAAAGAAGGAACGACAGCTCTGGGGATTGTTG
AAGCTGCCAAAGCTATAGGCTTTGAGACCCAAGCTGTTCGAGCTGATATGAGCCTCTTTGACGAAAAGGATATCCCTTTT
CCTTTTATCGTCCATGTCAATAAAGAAGGAAAACTGCAACACTACTATGTAGTTTACAAGGCCAAGAAAAATCACTTCAT
TATTGGTGATCCTGATCCTACAGTCAAGGTTACCAAAATGAAGAAAGAAACCTTTGAAAAAGAATGGGACGGTGTTTCCA
TCTTCTTAGCTCCAGAACCTGCTTACAAACCTCATAAGGATAGGAAAAATGGTTTACTGAATTTTATCCCCCTTATCCTG
AAGCAAAAGGGACTTATCTTTCAGATTAGCCTTGCTAGTCTTTTAGTAACCCTAATTGATATTCTAGGTTCCTACTACCT
CCAAGGTATTTTGGACAACTATATCCCCAATCAGATGCTGTCGACTCTGACTATCGTTTCGGTAGGTCTGGTCATTACCT
ATATTATCCAGCAAATCATGGCCTTCTCACGGGACTATCTCTTAACTGTCCTCAGTCAGAGACTTAGTATTGATGTGATT
TTAGCCTATATCCGCCACATTTTCTCTCTCCCTATGTCATTTTTTGCGACTAGACGGACGGGTGAGATTACCTCACGTTT
TTCGGATGCTAATGCCATCATTGATGCTCTCGCTTCGACCATCCTTTCCATCTTTCTGGATTGTTTTATCTTGATTATTA
TTGGGGCTGTCCTCTTTCTTCAAAATACGAATCTCTTTCTCTTGACCTTGCTGTCGATTCCAATCTATACCGTTATCATC
TTTGCTTTTATGAAGCCTTTTGAAAAGATGAACCAAGAGGTTATGGAAGCTAACAGTATGGTCAGCTCTGCTATTATCGA
AGATATCAATGGGATGGAAACCATTAAATCGCTGACCAGCGAAGACACGCGCTATCGCAATGTTGATAACGAGTTCGTTG
ACTATCTTGACAAATCTTTCAATCGTCATAAGTATGAAGTGCTGCAGACAGCTTTGAAAAAGGCTGCTCAGCTTATTTTA
AATGTCACCATCCTCTGGTTTGGCTCTAAACTAGTTATGTCCAATAGGATCTCTATCGGTCAGCTCATTGCCTATAACTC
GCTTTTAACCTACTTTACCAATCCATTGGAAAATATCATCAATTTGCAGACAAAACTGCAGTCAGCTAAAGTAGCCAACA
ACCGACTCAATGAAGTTTATCTTGTGTCATCGGAATTCGATAAAAAAACAACTAAGGTGGATCATTCAGCCTTAGATGGC
AAGATCGCTTTTTCAGATGTTTCCTATAAATATGGTTTTGGCCGTGATACTCTGACAGACATTAATCTTACAATTAATAG
GGGCTCAAAAATCAGTTTAGTTGGTATCAGTGGCTCCGGTAAAACAACATTGGCCAAACTGATTGTCAACTTCTTCCAAC
CATACAAGGGAGAAATCACCATTAATGGGCTAAATACTAATCTCTTGGATAAGAAGCTATTGCGGCGCTATATCAATTAT
CTACCCCAACAACCTTATATCTTTTCTGGCAGTATTTTAGACAACCTGACTCTAGGAGCAGATGAATCTGTTTCACAAGA
AGATATTATGAAAGCCTGTGAATTGGCTGAAATCAGAAGAGATATCGAGCAGATGCCCCTTGGCTATCAAACGGAATTAT
CTGATGGAGCCGGTCTATCTGGCGGTCAAAAGCAGAGGATCGCACTGGCCCGCGCCCTACTGACCAAGTCTCCGATTATG
GTTTTAGATGAAGCTACCAGCGGGCTGGATGTCTTAACTGAGAAAAAAGTCATTGACAACCTGATGCAGATGACGGAGAA
AACAATTATCTTCGTGGCTCACCGACTTAGCATTTCCGAGCGAACAGACAAAATCGTTGTTCTTGATCAGGGAAAAATCA
TAGAATCAGGTTCTCATCAAGATCTACTAAAAAAACAAGGTTTCTACTATCAACTCTTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (170-436)

• Peptidase C39 family (Peptidase_C39) (4-140)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.449	99.441	0.71
comA	Streptococcus mitis NCTC 12261	67.503	100	0.677
comA	Streptococcus mitis SK321	67.085	100	0.673
comA	Streptococcus pneumoniae Rx1	66.667	100	0.669
comA	Streptococcus pneumoniae D39	66.667	100	0.669
comA	Streptococcus pneumoniae R6	66.667	100	0.669
comA	Streptococcus pneumoniae TIGR4	66.388	100	0.666
comA	Streptococcus gordonii str. Challis substr. CH1	64.714	100	0.649