Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACFSN5_RS03975 Genome accession   NZ_CP172427
Coordinates   853921..854595 (+) Length   224 a.a.
NCBI ID   WP_165213431.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 848921..859595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS03960 (ACFSN5_03960) pstB 848931..849689 (+) 759 WP_398601069.1 phosphate ABC transporter ATP-binding protein PstB -
  ACFSN5_RS03965 (ACFSN5_03965) phoU 849725..850378 (+) 654 WP_398601071.1 phosphate signaling complex protein PhoU -
  ACFSN5_RS03970 (ACFSN5_03970) - 850478..853030 (+) 2553 WP_165213429.1 M1 family metallopeptidase -
  ACFSN5_RS03975 (ACFSN5_03975) ciaR 853921..854595 (+) 675 WP_165213431.1 response regulator transcription factor Regulator
  ACFSN5_RS03980 (ACFSN5_03980) ciaH 854585..855970 (+) 1386 WP_165213433.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACFSN5_RS03985 (ACFSN5_03985) - 856222..857394 (+) 1173 WP_398600534.1 IS110 family transposase -
  ACFSN5_RS03990 (ACFSN5_03990) rpsT 858197..858445 (-) 249 WP_206221365.1 30S ribosomal protein S20 -
  ACFSN5_RS03995 (ACFSN5_03995) coaA 858498..859418 (-) 921 WP_165212758.1 type I pantothenate kinase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25376.10 Da        Isoelectric Point: 4.2604

>NTDB_id=1067667 ACFSN5_RS03975 WP_165213431.1 853921..854595(+) (ciaR) [Streptococcus sp. ZJ 1593]
MIKILLVEDDLSLSNSVFDFLDDFAEVTQVFDGEEGLFEAETGVYDLILLDLMLPEKDGFTVLKELRDKGIPTPVLITTA
KEALDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKINDKLLTYGNLDCDTSTNTVTVDGKVVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTVSVVEVYVSKIRKKLKGTDFEQNLQTLRSVGYILKDVQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1067667 ACFSN5_RS03975 WP_165213431.1 853921..854595(+) (ciaR) [Streptococcus sp. ZJ 1593]
ATGATTAAAATTTTATTAGTAGAAGATGACCTTAGCCTTTCAAATTCTGTTTTCGATTTTTTGGATGACTTTGCTGAAGT
TACTCAAGTTTTCGATGGGGAGGAAGGCCTCTTTGAAGCAGAAACTGGTGTTTATGATTTGATTCTGCTCGATTTGATGT
TGCCGGAAAAAGATGGTTTTACTGTCTTGAAAGAGCTGCGTGACAAAGGTATCCCAACCCCTGTCTTGATTACAACTGCT
AAAGAAGCTTTGGATGATAAAGGACATGGTTTTGAACTCGGTGCCGATGACTACTTGACCAAGCCATTCTATTTGGAAGA
ATTGAAAATGCGGATTCAAGCACTCTTGAAGCGTTCTGGTAAAATCAATGATAAGCTTCTTACTTACGGAAATTTAGATT
GTGATACGTCAACTAATACGGTAACCGTTGATGGTAAAGTTGTTGAACTTTTAGGTAAAGAATTTGATCTTTTGGTTTAT
TTCCTTCAAAACCAAAATGTTATTTTGCCTAAGACACAAATTTTCGATCGCATTTGGGGGTTTGACAGCGATACAACTGT
CTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGTAAAAAGCTCAAAGGAACAGATTTCGAGCAAAACTTGCAAACACTAC
GTAGTGTGGGGTATATCTTAAAGGATGTTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

85.714

100

0.857
  ciaR Streptococcus pneumoniae D39

85.714

100

0.857
  ciaR Streptococcus pneumoniae R6

85.714

100

0.857
  ciaR Streptococcus pneumoniae TIGR4

85.714

100

0.857
  ciaR Streptococcus mutans UA159

85.714

100

0.857
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.889

100

0.371

Multiple sequence alignment