Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACFSN5_RS03980 Genome accession   NZ_CP172427
Coordinates   854585..855970 (+) Length   461 a.a.
NCBI ID   WP_165213433.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 849585..860970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS03965 (ACFSN5_03965) phoU 849725..850378 (+) 654 WP_398601071.1 phosphate signaling complex protein PhoU -
  ACFSN5_RS03970 (ACFSN5_03970) - 850478..853030 (+) 2553 WP_165213429.1 M1 family metallopeptidase -
  ACFSN5_RS03975 (ACFSN5_03975) ciaR 853921..854595 (+) 675 WP_165213431.1 response regulator transcription factor Regulator
  ACFSN5_RS03980 (ACFSN5_03980) ciaH 854585..855970 (+) 1386 WP_165213433.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACFSN5_RS03985 (ACFSN5_03985) - 856222..857394 (+) 1173 WP_398600534.1 IS110 family transposase -
  ACFSN5_RS03990 (ACFSN5_03990) rpsT 858197..858445 (-) 249 WP_206221365.1 30S ribosomal protein S20 -
  ACFSN5_RS03995 (ACFSN5_03995) coaA 858498..859418 (-) 921 WP_165212758.1 type I pantothenate kinase -
  ACFSN5_RS04000 (ACFSN5_04000) - 859482..860072 (+) 591 WP_165212760.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 461 a.a.        Molecular weight: 51931.95 Da        Isoelectric Point: 4.7331

>NTDB_id=1067668 ACFSN5_RS03980 WP_165213433.1 854585..855970(+) (ciaH) [Streptococcus sp. ZJ 1593]
MFNKLKKGLFSEGFSTFLHFLSVFTVIFLVMTILILQIMRIGIYSSVDDNLDKAAESVNSYIYMNMYKASLYSAFDGNDD
SDLSIFTDGDDFLGNGTTLPADANASGSPEQNKSHVELNATIETVMYDKNGKVLNSSEIFSGLNKLKMNRDELGDVNEVS
IDGSFREKEHYRYKTIAVSDKQFPKVAYVTIAISVNQLDSVNSRYQIIIISVMVTFWLLSVFASVYLANWSRKPIVESYE
RQKNFVEDASHELRTPLTVLQNRLESLFRKPDQTILDNYETIASSLEEVRNMRILTTNLLNLARRDDHLNPNIEEIEPAF
FDSIFENYQMIAEENGKSLTCRNQLDLPMKSDKTLIKQVMTILFDNAVKYTGEDGAIDISVTSEAGKMLISVADNGAGIS
EEDKIKIFDRFYRIDKARNRQTGGFGLGLSLAKQIVDALKGTISVRDNEPTGTIFEIKLSA

Nucleotide


Download         Length: 1386 bp        

>NTDB_id=1067668 ACFSN5_RS03980 WP_165213433.1 854585..855970(+) (ciaH) [Streptococcus sp. ZJ 1593]
ATGTTCAATAAGTTAAAGAAGGGTCTCTTTTCTGAAGGATTCTCGACTTTTCTTCACTTCCTATCTGTCTTCACCGTAAT
TTTCTTGGTGATGACCATTTTGATTTTGCAAATCATGCGGATTGGGATTTATTCATCAGTTGATGACAACCTCGATAAGG
CAGCTGAAAGTGTTAACTCCTATATCTATATGAATATGTATAAGGCGAGTCTTTACTCAGCCTTTGATGGTAATGATGAT
TCAGATCTCTCCATCTTTACTGATGGGGATGATTTTTTGGGAAATGGGACGACTCTTCCCGCTGATGCAAATGCTTCAGG
TAGTCCAGAACAAAACAAATCCCATGTGGAATTGAATGCTACGATTGAAACAGTCATGTATGATAAAAATGGCAAGGTAC
TCAATAGCTCAGAAATTTTTTCCGGACTGAACAAACTGAAAATGAATCGGGATGAACTGGGTGATGTCAACGAGGTTAGT
ATTGATGGTAGTTTTCGCGAGAAGGAACACTACCGCTATAAGACCATTGCGGTATCAGACAAGCAATTTCCTAAGGTTGC
TTATGTCACTATTGCCATTAGCGTCAATCAGCTGGATAGTGTTAATTCTCGTTATCAAATTATCATTATATCGGTGATGG
TAACCTTCTGGCTATTGTCAGTCTTTGCCAGTGTCTATCTGGCCAATTGGTCACGTAAGCCGATTGTGGAAAGTTATGAA
AGGCAAAAGAATTTTGTTGAGGATGCCAGTCATGAATTGCGGACACCTCTGACGGTTTTGCAAAACCGTTTAGAGAGTCT
TTTTCGTAAGCCAGACCAAACGATTTTGGACAATTATGAAACTATTGCTTCTAGTTTGGAAGAAGTCCGGAATATGCGGA
TTTTAACTACCAATCTGTTGAATTTAGCTAGGCGAGATGATCATCTTAATCCTAACATTGAAGAAATTGAGCCAGCTTTC
TTTGACAGTATTTTTGAGAATTACCAAATGATTGCTGAGGAAAATGGCAAAAGTTTAACCTGTCGTAATCAGCTTGATTT
ACCGATGAAATCTGATAAGACATTAATTAAGCAAGTCATGACCATTCTCTTTGATAATGCTGTTAAGTACACAGGAGAAG
ATGGGGCTATTGATATTAGCGTTACTAGCGAAGCAGGCAAAATGCTTATCTCAGTTGCGGATAATGGGGCTGGTATTAGC
GAGGAAGATAAGATAAAGATTTTTGACCGCTTTTACCGGATTGATAAAGCTCGCAATCGTCAGACCGGTGGTTTTGGCTT
AGGGCTATCTTTAGCTAAGCAGATTGTGGATGCCTTGAAAGGAACTATCTCTGTTCGTGATAATGAACCGACAGGAACTA
TTTTTGAAATTAAATTAAGCGCTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(352-459)

His Kinase A (phospho-acceptor) domain (HisKA)

(242-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

52.711

100

0.527
  ciaH Streptococcus pneumoniae Rx1

46.638

100

0.466
  ciaH Streptococcus pneumoniae D39

46.638

100

0.466
  ciaH Streptococcus pneumoniae R6

46.638

100

0.466
  ciaH Streptococcus pneumoniae TIGR4

46.638

100

0.466

Multiple sequence alignment