Detailed information NTG0106541

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: AABA16_RS09605
• Genome accession: NZ_AP028610
• Coordinates: 1853983..1854285 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep5
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1848983..1859285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA16_RS09570 (TKY124516_18610)	rnpA	1849663..1850034 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AABA16_RS09575	-	1850051..1850182 (-)	132	WP_000768904.1	hypothetical protein	-
AABA16_RS09580 (TKY124516_18620)	-	1850183..1851373 (-)	1191	WP_000167768.1	acetate kinase	-
AABA16_RS09585 (TKY124516_18630)	comYH	1851424..1852377 (-)	954	WP_000345086.1	class I SAM-dependent methyltransferase	Machinery gene
AABA16_RS09590	-	1852438..1853032 (-)	595	Protein_1863	methyltransferase domain-containing protein	-
AABA16_RS09595 (TKY124516_18660)	comGG/cglG	1853135..1853581 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABA16_RS09600 (TKY124516_18670)	comGF/cglF	1853559..1854020 (-)	462	WP_000250523.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABA16_RS09605 (TKY124516_18680)	comGE/cglE	1853983..1854285 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABA16_RS09610 (TKY124516_18690)	comGD/cglD	1854248..1854652 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABA16_RS09615 (TKY124516_18700)	comGC/cglC	1854645..1854971 (-)	327	WP_000738621.1	comG operon protein ComGC	Machinery gene
AABA16_RS09620 (TKY124516_18710)	comGB/cglB	1854973..1855989 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABA16_RS09625 (TKY124516_18720)	comGA/cglA/cilD	1855937..1856878 (-)	942	WP_000249568.1	competence type IV pilus ATPase ComGA	Machinery gene
AABA16_RS09630 (TKY124516_18730)	-	1856954..1857319 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABA16_RS09635 (TKY124516_18740)	-	1857470..1858528 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=106541 AABA16_RS09605 WP_000413380.1 1853983..1854285(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep5]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=106541 AABA16_RS09605 WP_000413380.1 1853983..1854285(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep5]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39