Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACHWYG_RS06480 Genome accession   NZ_CP172082
Coordinates   1290303..1291646 (-) Length   447 a.a.
NCBI ID   WP_032823983.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA54827     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1285303..1296646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYG_RS06450 - 1286221..1286493 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  ACHWYG_RS06455 - 1286634..1287224 (-) 591 WP_012055028.1 YjaG family protein -
  ACHWYG_RS06460 nudC 1287260..1288054 (-) 795 WP_032823981.1 NAD(+) diphosphatase -
  ACHWYG_RS06465 nfuA 1288121..1288717 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  ACHWYG_RS06470 - 1288793..1289479 (-) 687 WP_032823982.1 ComF family protein -
  ACHWYG_RS06475 tnpA 1289851..1290306 (-) 456 WP_005652127.1 IS200/IS605 family transposase -
  ACHWYG_RS06480 comE 1290303..1291646 (-) 1344 WP_032823983.1 type IV pilus secretin PilQ Machinery gene
  ACHWYG_RS06485 comD 1291656..1292069 (-) 414 WP_032823984.1 pilus assembly protein PilP Machinery gene
  ACHWYG_RS06490 comC 1292066..1292587 (-) 522 WP_032823985.1 competence protein ComC Machinery gene
  ACHWYG_RS06495 comB 1292584..1293090 (-) 507 WP_005649305.1 competence protein ComB Machinery gene
  ACHWYG_RS06500 comA 1293091..1293888 (-) 798 WP_032823986.1 pilus assembly protein PilM Machinery gene
  ACHWYG_RS06505 - 1293987..1296587 (+) 2601 WP_032823987.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49328.60 Da        Isoelectric Point: 7.1111

>NTDB_id=1065020 ACHWYG_RS06480 WP_032823983.1 1290303..1291646(-) (comE) [Haemophilus influenzae strain GA54827]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLDVLKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=1065020 ACHWYG_RS06480 WP_032823983.1 1290303..1291646(-) (comE) [Haemophilus influenzae strain GA54827]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACATTAGAGCAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAAGG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTAGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGCGCTTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACGTCGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCGCATAT
TTTAAAAGCGGGGGAAACGTTAGATGTTTTGAAACAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

96.18

99.553

0.957
  comE Haemophilus influenzae Rd KW20

95.955

99.553

0.955
  comE Glaesserella parasuis strain SC1401

52.471

95.078

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

93.736

0.403
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.17

0.389
  pilQ Vibrio cholerae strain A1552

42.233

92.17

0.389

Multiple sequence alignment