Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   ACHWYG_RS06495 Genome accession   NZ_CP172082
Coordinates   1292584..1293090 (-) Length   168 a.a.
NCBI ID   WP_005649305.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA54827     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1287584..1298090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYG_RS06465 nfuA 1288121..1288717 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  ACHWYG_RS06470 - 1288793..1289479 (-) 687 WP_032823982.1 ComF family protein -
  ACHWYG_RS06475 tnpA 1289851..1290306 (-) 456 WP_005652127.1 IS200/IS605 family transposase -
  ACHWYG_RS06480 comE 1290303..1291646 (-) 1344 WP_032823983.1 type IV pilus secretin PilQ Machinery gene
  ACHWYG_RS06485 comD 1291656..1292069 (-) 414 WP_032823984.1 pilus assembly protein PilP Machinery gene
  ACHWYG_RS06490 comC 1292066..1292587 (-) 522 WP_032823985.1 competence protein ComC Machinery gene
  ACHWYG_RS06495 comB 1292584..1293090 (-) 507 WP_005649305.1 competence protein ComB Machinery gene
  ACHWYG_RS06500 comA 1293091..1293888 (-) 798 WP_032823986.1 pilus assembly protein PilM Machinery gene
  ACHWYG_RS06505 - 1293987..1296587 (+) 2601 WP_032823987.1 penicillin-binding protein 1A -
  ACHWYG_RS06510 - 1296664..1297509 (+) 846 WP_032823988.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ACHWYG_RS06515 - 1297662..1297991 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19724.61 Da        Isoelectric Point: 8.5473

>NTDB_id=1065023 ACHWYG_RS06495 WP_005649305.1 1292584..1293090(-) (comB) [Haemophilus influenzae strain GA54827]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=1065023 ACHWYG_RS06495 WP_005649305.1 1292584..1293090(-) (comB) [Haemophilus influenzae strain GA54827]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

99.405

100

0.994
  comB Haemophilus influenzae Rd KW20

99.405

100

0.994

Multiple sequence alignment