Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACHWYG_RS05460 Genome accession   NZ_CP172082
Coordinates   1119231..1120451 (-) Length   406 a.a.
NCBI ID   WP_032823890.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA54827     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1114231..1125451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYG_RS05420 - 1115137..1115343 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACHWYG_RS05425 - 1115417..1115623 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  ACHWYG_RS05430 - 1115697..1115903 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACHWYG_RS05435 - 1115977..1116183 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  ACHWYG_RS05440 cueR 1116260..1116646 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  ACHWYG_RS05445 metJ 1116660..1116977 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  ACHWYG_RS05450 rho 1117225..1118487 (+) 1263 WP_005666690.1 transcription termination factor Rho -
  ACHWYG_RS05455 pilD 1118542..1119234 (-) 693 WP_032823889.1 A24 family peptidase Machinery gene
  ACHWYG_RS05460 pilC 1119231..1120451 (-) 1221 WP_032823890.1 type II secretion system F family protein Machinery gene
  ACHWYG_RS05465 pilB 1120448..1121839 (-) 1392 WP_032823891.1 GspE/PulE family protein Machinery gene
  ACHWYG_RS05470 pilA 1121836..1122276 (-) 441 WP_032823893.1 prepilin peptidase-dependent pilin Machinery gene
  ACHWYG_RS05475 ampD 1122391..1122951 (+) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACHWYG_RS05480 corC 1123574..1124473 (+) 900 WP_032823895.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46164.42 Da        Isoelectric Point: 9.7213

>NTDB_id=1065012 ACHWYG_RS05460 WP_032823890.1 1119231..1120451(-) (pilC) [Haemophilus influenzae strain GA54827]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISCGLTHIKLQQNWQFVAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1065012 ACHWYG_RS05460 WP_032823890.1 1119231..1120451(-) (pilC) [Haemophilus influenzae strain GA54827]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGTGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTTAATCAATTAGCGACACTACTACAATCTGCCATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATCCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAAACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment