Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACG3JK_RS05785 Genome accession   NZ_CP171738
Coordinates   1157986..1158741 (-) Length   251 a.a.
NCBI ID   WP_004234185.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M23     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152986..1163741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JK_RS05765 (ACG3JK_05765) - 1153325..1154551 (-) 1227 WP_045407467.1 cysteine desulfurase -
  ACG3JK_RS05770 (ACG3JK_05770) sufD 1154576..1155838 (-) 1263 WP_003102572.1 Fe-S cluster assembly protein SufD -
  ACG3JK_RS05775 (ACG3JK_05775) sufC 1155927..1156697 (-) 771 WP_004234182.1 Fe-S cluster assembly ATPase SufC -
  ACG3JK_RS05780 (ACG3JK_05780) - 1156822..1157979 (-) 1158 WP_013794310.1 glycosyltransferase family 4 protein -
  ACG3JK_RS05785 (ACG3JK_05785) mecA 1157986..1158741 (-) 756 WP_004234185.1 adaptor protein MecA Regulator
  ACG3JK_RS05790 (ACG3JK_05790) - 1158845..1159684 (-) 840 WP_003108565.1 undecaprenyl-diphosphate phosphatase -
  ACG3JK_RS05795 (ACG3JK_05795) - 1159758..1161662 (-) 1905 WP_045407474.1 DUF2207 domain-containing protein -
  ACG3JK_RS05800 (ACG3JK_05800) - 1161868..1163436 (+) 1569 WP_004234187.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29155.84 Da        Isoelectric Point: 4.1299

>NTDB_id=1064076 ACG3JK_RS05785 WP_004234185.1 1157986..1158741(-) (mecA) [Streptococcus parauberis strain DB-M23]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKDINFEDLAELGDISQMTPEDFFKTIEKNMMEKGDVDAHQKLEKIEEMLEDASAQAQEQAKVAEQEEYEAEVLDYVHFV
LSFASIEDAINFSKTIDFPIEASELYKESKSYHMTILLDVQNQPSYYANVSYARLIEHANPGIRTRAYLQEHGIQLIEDN
AVEELKKIEMV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1064076 ACG3JK_RS05785 WP_004234185.1 1157986..1158741(-) (mecA) [Streptococcus parauberis strain DB-M23]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATAACAATCAGCATGGATGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCACAAGAAAAGACCGAAGAATTTTTCTATTCAGTTATGGATGAACTTGATTTACCAGAAAACT
TTAAAGATAGTGGTATGCTTAGTTTCAGAGTGACACCTCGAAAAGACCGATTAGATGTCTTTGTTACAAAATCAGAATTA
AGTAAAGACATCAATTTTGAAGATTTAGCTGAACTAGGTGATATTTCACAAATGACGCCTGAAGATTTTTTCAAAACGAT
TGAAAAAAACATGATGGAAAAAGGTGATGTCGATGCTCACCAAAAATTAGAGAAAATTGAAGAAATGCTTGAGGATGCCT
CTGCTCAGGCGCAGGAGCAAGCAAAAGTTGCTGAACAAGAAGAGTATGAAGCAGAAGTTCTTGATTATGTTCACTTCGTA
TTGAGTTTTGCTTCTATTGAAGATGCAATTAATTTTTCAAAAACAATTGATTTCCCAATTGAAGCATCTGAGTTATATAA
GGAAAGCAAAAGTTATCACATGACTATTTTATTAGATGTTCAAAATCAACCTTCATATTATGCAAATGTTAGCTATGCAC
GTTTAATTGAACATGCTAATCCTGGGATTAGGACCAGAGCTTATTTACAGGAGCATGGCATTCAATTAATTGAAGATAAT
GCTGTTGAAGAATTGAAAAAAATTGAGATGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.113

98.805

0.633
  mecA Streptococcus thermophilus LMD-9

56.855

98.805

0.562
  mecA Streptococcus thermophilus LMG 18311

56.048

98.805

0.554
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.482
  mecA Streptococcus pneumoniae D39

47.826

100

0.482
  mecA Streptococcus pneumoniae R6

47.826

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.826

100

0.482

Multiple sequence alignment