Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACG3JE_RS09825 Genome accession   NZ_CP171736
Coordinates   1933764..1934972 (+) Length   402 a.a.
NCBI ID   WP_003108843.1    Uniprot ID   A0A0E2UDP0
Organism   Streptococcus parauberis strain DB-M17     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928764..1939972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JE_RS09800 (ACG3JE_09800) - 1929975..1932553 (+) 2579 Protein_1906 YfhO family protein -
  ACG3JE_RS09820 (ACG3JE_09820) rlmH 1933081..1933560 (-) 480 WP_013794545.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACG3JE_RS09825 (ACG3JE_09825) htrA 1933764..1934972 (+) 1209 WP_003108843.1 S1C family serine protease Regulator
  ACG3JE_RS09830 (ACG3JE_09830) spo0J 1935048..1935821 (+) 774 WP_045407580.1 ParB/RepB/Spo0J family partition protein Regulator
  ACG3JE_RS09835 (ACG3JE_09835) dnaA 1936058..1937418 (+) 1361 Protein_1910 chromosomal replication initiator protein DnaA -
  ACG3JE_RS09840 (ACG3JE_09840) dnaN 1937574..1938710 (+) 1137 WP_003103000.1 DNA polymerase III subunit beta -
  ACG3JE_RS09845 (ACG3JE_09845) - 1938781..1938978 (+) 198 WP_003104619.1 DUF951 domain-containing protein -
  ACG3JE_RS09850 (ACG3JE_09850) - 1939099..1939467 (+) 369 WP_003107958.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 42581.09 Da        Isoelectric Point: 4.9341

>NTDB_id=1063999 ACG3JE_RS09825 WP_003108843.1 1933764..1934972(+) (htrA) [Streptococcus parauberis strain DB-M17]
MSKLKSVLKVFLYLLAGFIGGVMAFFIMNSIKPTQQSDNDNVSKTTSTSKVTYNNTTSTTKAVKKVQDAVVSVINYQKID
TASSDNYNSLFGDSSESKQTDDGLAIFSEGSGVIYKKDGKDAYIVTNNHVIDGAKRIEILLADGSKIVGTLIGSDTYSDL
AVVKVSSEKIKSVAKFADSTKINIGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNEEGKTVSTNAIQTDAAINPGN
SGGALINVEGQVIGINSSKISSTNEAGGAVEGMGFAIPSNDVVKIINQLEEKGEVIRPALGISMVNLGDLSTSALSQLNV
PKEVTSGIVVATVTEDMPATDKLKQYDIITAIDGEEVKTTSDLQSALYGHDINDEVKITFYRGNEKKTVTVKLTKTTKDL
EK

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=1063999 ACG3JE_RS09825 WP_003108843.1 1933764..1934972(+) (htrA) [Streptococcus parauberis strain DB-M17]
GTGTCAAAATTAAAAAGTGTTCTGAAAGTATTTCTTTATTTATTAGCTGGATTTATAGGGGGAGTAATGGCGTTCTTTAT
CATGAATTCTATTAAACCAACGCAACAATCAGATAATGATAATGTTTCAAAAACAACCAGCACAAGTAAAGTTACCTATA
ATAATACGACAAGTACTACTAAAGCAGTTAAGAAAGTTCAAGATGCAGTTGTTTCTGTTATCAACTATCAAAAGATAGAT
ACTGCTTCATCTGATAACTACAATAGTCTTTTTGGAGATAGTAGTGAATCTAAACAAACTGATGATGGTTTAGCAATTTT
CAGTGAAGGATCTGGAGTTATCTACAAAAAAGATGGTAAAGATGCTTATATCGTTACCAATAATCACGTTATTGATGGTG
CAAAACGGATTGAAATTTTACTTGCTGATGGCTCTAAAATCGTAGGTACACTCATCGGTTCAGATACTTATTCAGATTTA
GCAGTTGTAAAAGTGTCTTCAGAAAAAATCAAATCAGTTGCTAAATTTGCTGACTCAACAAAAATTAATATTGGAGAAGT
TGCCATTGCAATTGGTAGCCCTCTTGGAACAGAATATGCAAACTCAGTTACTGAGGGGATTGTTTCAAGTTTAAGTCGTA
CTGTTACCTTGAAAAATGAAGAAGGTAAAACCGTTTCAACAAATGCTATCCAAACGGACGCAGCTATTAACCCAGGTAAT
TCTGGAGGAGCACTTATTAATGTTGAAGGACAAGTAATTGGAATTAACTCAAGTAAAATTTCATCAACAAATGAAGCTGG
TGGAGCAGTTGAAGGTATGGGATTTGCAATTCCTTCTAATGATGTTGTCAAAATTATTAATCAACTTGAAGAAAAAGGTG
AAGTTATTAGACCAGCCCTTGGTATCTCAATGGTAAATCTTGGTGATCTTTCTACAAGTGCTTTATCGCAATTAAATGTA
CCTAAAGAAGTTACAAGTGGTATCGTCGTAGCAACTGTTACTGAAGATATGCCTGCTACTGATAAACTTAAACAATATGA
TATCATTACAGCTATTGACGGTGAAGAAGTTAAAACAACAAGTGATTTACAAAGTGCTCTTTACGGCCATGATATCAATG
ATGAGGTAAAAATCACCTTCTATCGTGGTAATGAAAAGAAAACTGTTACTGTTAAATTAACTAAAACAACTAAAGATTTA
GAAAAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(110-255)

PDZ domain (PDZ_2)

(298-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UDP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.224

97.512

0.597
  htrA Streptococcus gordonii str. Challis substr. CH1

55.416

98.756

0.547
  htrA Streptococcus mitis NCTC 12261

53.431

100

0.542
  htrA Streptococcus pneumoniae Rx1

53.448

100

0.54
  htrA Streptococcus pneumoniae D39

53.448

100

0.54
  htrA Streptococcus pneumoniae R6

53.448

100

0.54
  htrA Streptococcus pneumoniae TIGR4

53.448

100

0.54

Multiple sequence alignment