Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ACG3JE_RS02745 Genome accession   NZ_CP171736
Coordinates   499472..500182 (+) Length   236 a.a.
NCBI ID   WP_013793732.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M17     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 494472..505182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JE_RS02720 (ACG3JE_02720) - 495207..496214 (+) 1008 WP_003106351.1 DUF3114 domain-containing protein -
  ACG3JE_RS02725 (ACG3JE_02725) - 496237..496884 (-) 648 WP_003104005.1 amino acid ABC transporter permease -
  ACG3JE_RS02730 (ACG3JE_02730) - 496899..497603 (-) 705 WP_003104614.1 amino acid ABC transporter permease -
  ACG3JE_RS02735 (ACG3JE_02735) - 497617..498432 (-) 816 WP_013793731.1 transporter substrate-binding domain-containing protein -
  ACG3JE_RS02740 (ACG3JE_02740) - 498445..499224 (-) 780 WP_003106355.1 amino acid ABC transporter ATP-binding protein -
  ACG3JE_RS02745 (ACG3JE_02745) vicR 499472..500182 (+) 711 WP_013793732.1 response regulator YycF Regulator
  ACG3JE_RS02750 (ACG3JE_02750) vicK 500175..501535 (+) 1361 Protein_517 cell wall metabolism sensor histidine kinase VicK -
  ACG3JE_RS02755 (ACG3JE_02755) vicX 501540..502349 (+) 810 WP_037619792.1 MBL fold metallo-hydrolase Regulator
  ACG3JE_RS02760 (ACG3JE_02760) rnc 502447..503139 (+) 693 WP_003103277.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26996.81 Da        Isoelectric Point: 4.8271

>NTDB_id=1063975 ACG3JE_RS02745 WP_013793732.1 499472..500182(+) (vicR) [Streptococcus parauberis strain DB-M17]
MKKVLIVDDEKPISDIIKFNLTKEGYDTITAFDGREAVTAFEEEKPDLVILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENAISGTQELTIGNLQILPDAFVAKKYGDEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKAHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1063975 ACG3JE_RS02745 WP_013793732.1 499472..500182(+) (vicR) [Streptococcus parauberis strain DB-M17]
ATGAAAAAAGTTCTGATTGTCGATGATGAAAAGCCAATTTCAGATATCATCAAATTCAATTTAACAAAAGAAGGGTATGA
TACAATTACTGCCTTTGATGGGCGTGAAGCTGTAACTGCTTTTGAAGAAGAAAAACCTGACTTAGTTATTCTCGACTTAA
TGCTTCCTGAGTTGGATGGTCTTGAAGTAGCTAAGGAAATTCGCAAAACAAGTCATATCCCTATTATTATGCTTTCTGCT
AAAGATAGTGAATTTGATAAAGTTATTGGGCTTGAAATCGGTGCAGATGACTATGTGACCAAACCTTTTTCAAATCGTGA
ATTATTAGCCCGTGTAAAAGCTCATTTACGAAGAACTGAGACGATTGAAACAGCAGTCGCAGAGGAAAATGCTATCTCTG
GTACACAAGAATTAACTATCGGAAATTTACAAATTCTTCCGGATGCCTTTGTTGCCAAAAAATATGGTGATGAAGTTGAG
CTTACCCATCGTGAATTTGAATTGTTGCATCATTTAGCAAATCACATTGGTCAAGTTATGACTCGTGAGCACCTGCTTGA
AACGGTTTGGGGTTATGATTATTTTGGCGATGTTCGAACTGTCGATGTAACTGTTCGTCGTTTGAGAGAAAAAATTGAAG
ATACGCCTAGCCGTCCTGAATACATTTTGACAAGACGTGGTGTTGGCTATTATATGAAGGCGCATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.407

100

0.894
  micA Streptococcus pneumoniae Cp1015

77.872

99.576

0.775
  covR Streptococcus salivarius strain HSISS4

43.777

98.729

0.432
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.103

98.305

0.424
  scnR Streptococcus mutans UA159

36.975

100

0.373

Multiple sequence alignment