Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACG3JE_RS01630 Genome accession   NZ_CP171736
Coordinates   300356..301153 (+) Length   265 a.a.
NCBI ID   WP_394714038.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M17     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 295356..306153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JE_RS01615 (ACG3JE_01615) - 295661..297229 (-) 1569 WP_004234187.1 ABC transporter substrate-binding protein/permease -
  ACG3JE_RS01620 (ACG3JE_01620) - 297435..299339 (+) 1905 WP_045407474.1 DUF2207 domain-containing protein -
  ACG3JE_RS01625 (ACG3JE_01625) - 299413..300252 (+) 840 WP_003108565.1 undecaprenyl-diphosphate phosphatase -
  ACG3JE_RS01630 (ACG3JE_01630) mecA 300356..301153 (+) 798 WP_394714038.1 adaptor protein MecA Regulator
  ACG3JE_RS01635 (ACG3JE_01635) - 301117..302274 (+) 1158 WP_013794310.1 glycosyltransferase family 4 protein -
  ACG3JE_RS01640 (ACG3JE_01640) sufC 302399..303169 (+) 771 WP_004234182.1 Fe-S cluster assembly ATPase SufC -
  ACG3JE_RS01645 (ACG3JE_01645) sufD 303258..304520 (+) 1263 WP_003102572.1 Fe-S cluster assembly protein SufD -
  ACG3JE_RS01650 (ACG3JE_01650) - 304545..305771 (+) 1227 WP_045407467.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 30846.99 Da        Isoelectric Point: 4.1787

>NTDB_id=1063966 ACG3JE_RS01630 WP_394714038.1 300356..301153(+) (mecA) [Streptococcus parauberis strain DB-M17]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKDINFEDLAELGDISQMTPEDFFKTIEKNMMEKGDVDAHQKLEKIEEMLEDASAQAQEQAKVAEQEEYEAEVLDYVHFV
LSFASIEDAINFSKTIDFPIEASELYKESKSYHMTILLDVQNQPSYYANVSYARLIEHANPGIRTRAYLQEHGIQLIEDN
AVEELKKLRWCNVVCFLLLLIIYLS

Nucleotide


Download         Length: 798 bp        

>NTDB_id=1063966 ACG3JE_RS01630 WP_394714038.1 300356..301153(+) (mecA) [Streptococcus parauberis strain DB-M17]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATAACAATCAGCATGGATGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCACAAGAAAAGACCGAAGAATTTTTCTATTCAGTTATGGATGAACTTGATTTACCAGAAAACT
TTAAAGATAGTGGTATGCTTAGTTTCAGAGTGACACCTCGAAAAGACCGATTAGATGTCTTTGTTACAAAATCAGAATTA
AGTAAAGACATCAATTTTGAAGATTTAGCTGAACTAGGTGATATTTCACAAATGACGCCTGAAGATTTTTTCAAAACGAT
TGAAAAAAACATGATGGAAAAAGGTGATGTCGATGCTCACCAAAAATTAGAGAAAATTGAAGAAATGCTTGAGGATGCCT
CTGCTCAGGCGCAGGAGCAAGCAAAAGTTGCTGAACAAGAAGAGTATGAAGCAGAAGTTCTTGATTATGTTCACTTCGTA
TTGAGTTTTGCTTCTATTGAAGATGCAATTAATTTTTCAAAAACAATTGATTTCCCAATTGAAGCATCTGAGTTATATAA
GGAAAGCAAAAGTTATCACATGACTATTTTATTAGATGTTCAAAATCAACCTTCATATTATGCAAATGTTAGCTATGCAC
GTTTAATTGAACATGCTAATCCTGGGATTAGGACCAGAGCTTATTTACAGGAGCATGGCATTCAATTAATTGAAGATAAT
GCTGTTGAAGAATTGAAAAAATTGAGATGGTGTAATGTTGTATGTTTCCTTTTACTTTTAATCATATACTTGTCCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.228

92.83

0.596
  mecA Streptococcus thermophilus LMD-9

56.126

95.472

0.536
  mecA Streptococcus thermophilus LMG 18311

55.336

95.472

0.528
  mecA Streptococcus pneumoniae Rx1

47.431

95.472

0.453
  mecA Streptococcus pneumoniae D39

47.431

95.472

0.453
  mecA Streptococcus pneumoniae R6

47.431

95.472

0.453
  mecA Streptococcus pneumoniae TIGR4

47.431

95.472

0.453

Multiple sequence alignment