Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   ACG3JH_RS10250 Genome accession   NZ_CP171731
Coordinates   2001237..2002976 (+) Length   579 a.a.
NCBI ID   WP_003107495.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M1     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1996237..2007976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JH_RS10235 (ACG3JH_10235) fmt 1998212..1999147 (+) 936 WP_013794216.1 methionyl-tRNA formyltransferase -
  ACG3JH_RS10240 (ACG3JH_10240) rsmB 1999137..2000459 (+) 1323 WP_003105444.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACG3JH_RS10245 (ACG3JH_10245) - 2000497..2001237 (+) 741 WP_003102848.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACG3JH_RS10250 (ACG3JH_10250) pknB 2001237..2002976 (+) 1740 WP_003107495.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACG3JH_RS10255 (ACG3JH_10255) liaF 2003127..2003822 (+) 696 WP_037620823.1 cell wall-active antibiotics response protein LiaF -
  ACG3JH_RS10260 (ACG3JH_10260) - 2003819..2004823 (+) 1005 WP_003107494.1 sensor histidine kinase -
  ACG3JH_RS10265 (ACG3JH_10265) - 2004816..2005457 (+) 642 WP_003107492.1 response regulator transcription factor -
  ACG3JH_RS10270 (ACG3JH_10270) - 2005491..2006891 (+) 1401 WP_045407608.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACG3JH_RS10275 (ACG3JH_10275) - 2006891..2007244 (+) 354 WP_003103672.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 579 a.a.        Molecular weight: 63723.38 Da        Isoelectric Point: 6.3653

>NTDB_id=1063752 ACG3JH_RS10250 WP_003107495.1 2001237..2002976(+) (pknB) [Streptococcus parauberis strain DB-M1]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKRFIQENAPIPNEQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKDGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENKGVP
QALENVVIKATAKRLSDRYATTFDMSRDLMTALSYNRSRERKLVFHDVESTKPLPKVTPVPVTQTKSSVAPQTSGSEIHD
DAVTPQKTKKKRGRLLGTLLKILFALFVVLVAVFAFLVLTKPSTVKVPNVNGTTLSVAKKELTDLGFQVGQIHKMEDTAV
DSGKVIKTDPKAGTERREGARIDLFVSTGQPKVKKKSKDKVLMPDFTNMTYKDVLNMLTNEYGIHPNRIVAYYQDAPNPE
NYSKVSSPKDSQLVMGQYPIVGTYYIISDKEDIELYLSPDSGDNTTVFSSTPTSTSSSSEEETSTSTETSTSSESTTSSS
SSDATTTDSTTSDTSTTTP

Nucleotide


Download         Length: 1740 bp        

>NTDB_id=1063752 ACG3JH_RS10250 WP_003107495.1 2001237..2002976(+) (pknB) [Streptococcus parauberis strain DB-M1]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGTATCCTGAAGTCTATTGGCCGCGGTGGTATGGCTGATGTATA
TTTAGCCAATGATTTGATATTAGATAATGAAGATGTTGCAATAAAAGTTTTGCGAACCAATTATCAGACGGATCAAGTAG
CAGTAGCTCGTTTCCAACGGGAAGCGCGTGCTATGGCTGAATTAAATCATCCAAACATCGTTGCAATTAGAGATATAGGG
GAAGAGGACGGACAGCAGTTCCTAGTAATGGAATATGTTGATGGATTTGATCTTAAACGATTTATCCAGGAAAATGCACC
AATTCCAAATGAACAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACTTTAGCCCATCAAAAAGGGATTGTTC
ATAGAGATTTAAAACCTCAAAATATCCTGCTAACTAAGGATGGAGTTGTCAAAGTTACAGACTTTGGGATCGCAGTTGCC
TTTGCTGAGACAAGTTTAACTCAGACAAATTCAATGCTAGGTAGTGTTCACTATCTTTCACCTGAACAAGCAAGAGGTTC
AAAAGCGACTATCCAAAGTGATATTTATGCCATGGGTATTATGTTGTTTGAAATGTTAACTGGTCATATTCCTTATGACG
GGGATAGTGCCGTAACAATTGCTTTACAACATTTCCAAAAACCACTGCCTTCAATTATTGAAGAAAATAAAGGTGTACCG
CAGGCTCTTGAGAATGTTGTTATTAAAGCGACAGCTAAGCGTTTAAGTGATCGATATGCGACTACTTTTGATATGAGCAG
AGATTTGATGACAGCGCTAAGCTATAATCGAAGCCGTGAACGGAAGTTAGTCTTCCATGATGTTGAAAGTACCAAGCCAC
TACCTAAAGTTACACCTGTTCCGGTTACGCAAACCAAATCATCTGTAGCACCTCAAACATCTGGATCTGAAATCCATGAT
GATGCGGTTACACCTCAAAAAACAAAGAAAAAACGTGGACGTCTTTTGGGAACTTTACTCAAAATTTTATTCGCCCTCTT
TGTTGTTTTGGTTGCTGTCTTTGCCTTTTTAGTCCTAACGAAGCCATCTACGGTGAAGGTTCCAAATGTGAATGGAACTA
CATTGAGTGTGGCCAAAAAAGAATTGACTGATTTAGGTTTCCAAGTTGGACAGATTCACAAAATGGAAGATACAGCAGTT
GATTCTGGTAAGGTCATTAAAACAGATCCTAAGGCAGGCACTGAGCGCCGTGAAGGGGCTCGGATTGATCTCTTTGTTTC
AACTGGACAACCTAAAGTTAAGAAGAAAAGTAAAGATAAAGTGTTAATGCCTGATTTTACGAATATGACTTACAAAGATG
TCCTTAATATGTTAACAAATGAGTATGGTATTCATCCAAATCGAATTGTTGCCTATTATCAAGATGCTCCGAATCCAGAA
AATTATTCCAAGGTAAGCTCACCAAAAGATTCACAACTTGTTATGGGACAATATCCAATAGTTGGTACTTATTACATTAT
TTCAGATAAGGAAGATATTGAACTTTATCTAAGTCCAGATTCTGGAGATAATACAACTGTATTCTCATCAACACCAACAT
CGACATCAAGTTCAAGTGAAGAGGAAACAAGTACAAGCACAGAAACTTCTACAAGCTCTGAATCAACAACAAGTTCAAGT
AGTAGTGATGCAACAACTACTGATTCAACGACTTCGGATACAAGTACTACTACACCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-234)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(441-518)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

60.984

98.273

0.599
  stkP/pknB Streptococcus salivarius strain HSISS4

66.528

83.074

0.553
  stkP Streptococcus pneumoniae TIGR4

61.872

75.648

0.468
  stkP Streptococcus pneumoniae D39

61.644

75.648

0.466
  stkP Streptococcus pneumoniae R6

61.644

75.648

0.466
  stkP Streptococcus pneumoniae Rx1

61.416

75.648

0.465

Multiple sequence alignment