Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   AABA07_RS00240 Genome accession   NZ_AP028608
Coordinates   44177..45526 (+) Length   449 a.a.
NCBI ID   WP_338172770.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep3     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 39177..50526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA07_RS00210 (TKY120829_00350) plsX 39296..40288 (+) 993 WP_000717463.1 phosphate acyltransferase PlsX -
  AABA07_RS00215 (TKY120829_00360) - 40294..40527 (+) 234 WP_000659555.1 acyl carrier protein -
  AABA07_RS00220 (TKY120829_00370) - 40573..40863 (+) 291 Protein_36 IS5/IS1182 family transposase -
  AABA07_RS00225 blpU 41066..41296 (+) 231 Protein_37 bacteriocin-like peptide BlpU -
  AABA07_RS00230 - 41299..41424 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  AABA07_RS00235 (TKY120829_00390) comA 42011..44164 (+) 2154 WP_000668304.1 peptide cleavage/export ABC transporter ComA Regulator
  AABA07_RS00240 (TKY120829_00400) comB 44177..45526 (+) 1350 WP_338172770.1 competence pheromone export protein ComB Regulator
  AABA07_RS00245 (TKY120829_00410) purC 45696..46403 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AABA07_RS00250 - 46405..46548 (+) 144 WP_050167432.1 hypothetical protein -
  AABA07_RS00255 (TKY120829_00420) - 46605..50330 (+) 3726 WP_000361187.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49602.49 Da        Isoelectric Point: 5.2477

>NTDB_id=106333 AABA07_RS00240 WP_338172770.1 44177..45526(+) (comB) [Streptococcus pneumoniae strain Sep3]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGTEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEIEGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=106333 AABA07_RS00240 WP_338172770.1 44177..45526(+) (comB) [Streptococcus pneumoniae strain Sep3]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGACAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAATAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCAACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.664

100

0.987
  comB Streptococcus pneumoniae Rx1

98.441

100

0.984
  comB Streptococcus pneumoniae D39

98.441

100

0.984
  comB Streptococcus pneumoniae R6

98.441

100

0.984
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment