Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AAA996_RS10640 Genome accession   NZ_AP028606
Coordinates   2070878..2071540 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain Sep1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2065878..2076540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS10615 (TKY121773_20520) - 2066028..2066294 (-) 267 WP_001278167.1 Veg family protein -
  AAA996_RS10620 (TKY121773_20530) dnaB 2066296..2067648 (-) 1353 WP_000852486.1 replicative DNA helicase -
  AAA996_RS10625 (TKY121773_20540) rplI 2067692..2068144 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  AAA996_RS10630 (TKY121773_20550) - 2068141..2070114 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  AAA996_RS10635 (TKY121773_20560) raiA 2070250..2070798 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  AAA996_RS10640 (TKY121773_20570) comFC/cflB 2070878..2071540 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  AAA996_RS10645 (TKY121773_20580) comFA/cflA 2071537..2072835 (-) 1299 WP_000867610.1 DEAD/DEAH box helicase Machinery gene
  AAA996_RS10650 (TKY121773_20590) - 2072891..2073526 (+) 636 WP_000395739.1 YigZ family protein -
  AAA996_RS10655 (TKY121773_20600) cysK 2073811..2074731 (+) 921 WP_000029862.1 cysteine synthase A -
  AAA996_RS10660 - 2074970..2075335 (-) 366 Protein_2061 IS66 family transposase -
  AAA996_RS10665 - 2075317..2075480 (+) 164 Protein_2062 transposase -
  AAA996_RS10670 (TKY121773_20620) tnpB 2075594..2075848 (-) 255 WP_078373100.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=106243 AAA996_RS10640 WP_000649971.1 2070878..2071540(-) (comFC/cflB) [Streptococcus pneumoniae strain Sep1]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=106243 AAA996_RS10640 WP_000649971.1 2070878..2071540(-) (comFC/cflB) [Streptococcus pneumoniae strain Sep1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment