Detailed information NTG1062369

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ACF0HZ_RS09590
• Genome accession: NZ_CP171619
• Coordinates: 1894727..1895866 (+)
• Length: 379 a.a.
• NCBI ID: WP_072614345.1
• Uniprot ID: -
• Organism: Leuconostoc suionicum strain VITA-PB2
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1889727..1900866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF0HZ_RS09570 (ACF0HZ_09585)	yycF	1889891..1890598 (+)	708	WP_010281559.1	response regulator YycF	-
ACF0HZ_RS09575 (ACF0HZ_09590)	walK	1890666..1892531 (+)	1866	WP_105299763.1	cell wall metabolism sensor histidine kinase WalK	-
ACF0HZ_RS09580 (ACF0HZ_09595)	-	1892521..1893813 (+)	1293	WP_072614347.1	hypothetical protein	-
ACF0HZ_RS09585 (ACF0HZ_09600)	yycI	1893872..1894666 (+)	795	WP_072614346.1	two-component system regulatory protein YycI	-
ACF0HZ_RS09590 (ACF0HZ_09605)	htrA	1894727..1895866 (+)	1140	WP_072614345.1	S1C family serine protease	Regulator
ACF0HZ_RS09595 (ACF0HZ_09610)	rlmH	1896497..1896976 (+)	480	WP_394455600.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ACF0HZ_RS09600 (ACF0HZ_09615)	-	1897070..1899235 (+)	2166	WP_394455602.1	YhgE/Pip family protein	-
ACF0HZ_RS09605 (ACF0HZ_09620)	-	1899289..1899759 (+)	471	WP_072614342.1	Rrf2 family transcriptional regulator	-
ACF0HZ_RS09610 (ACF0HZ_09625)	-	1899824..1900489 (-)	666	WP_072614341.1	NAD(P)H-hydrate epimerase	-

Sequence

Protein

• Length: 379 a.a.
• Molecular weight: 39216.53 Da
• Isoelectric Point: 9.9329

>NTDB_id=1062369 ACF0HZ_RS09590 WP_072614345.1 1894727..1895866(+) (htrA) [Leuconostoc suionicum strain VITA-PB2]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVETTSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTSVEGMGFAIPSDQVVDIVNKLVKNGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKNSLGDTITLTYYHQDTKKTVKVKLTQKLAS

Nucleotide

• Length: 1140 bp

>NTDB_id=1062369 ACF0HZ_RS09590 WP_072614345.1 1894727..1895866(+) (htrA) [Leuconostoc suionicum strain VITA-PB2]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAACAAGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTAAGTACGACAGCAACAAGTACAAAAACGATTGCCAAGA
ATGCAACCGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTAAACTTTACTAAATCTAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACAGATGGGTCGGCATTTATTGTAACGAATAATCA
CGTCATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCTACACTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAGATCGACGGCACAGACGTTACGACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAACGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGTATCATTTC
TGCCAAAAAAAGGTTAGTTGAGACGACATCTGAAAATGGGCAGAATTATGGTGGATCCACGGTTATTCAGACGGATGCTG
CCATTAACCCTGGTAACTCAGGGGGACCATTAATTAATTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTATCA
ACATCTTCTTCGGGAACGAGCGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAAATGGTAAGGTCACACGACCAGCAATCGGTATTAGTTTGATTAATTTGTCGGAAGTAACAGCTTCTGAGCAAA
AATCAACTTTGAAAATTCCAGATAGTGTTACTGGTGGTGTTGTAGTAATGAGTTTGACTAACAATGGCCCAGCGGATAAA
GCTGGATTGAAAAAGTACGATGTTATCGTTGGCATTAATGGTAAAAAGGTAAGTTCACAGGCTGATCTGCGAGAAGAACT
ATACAAGAATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGAAGACAGTCAAGGTTAAATTAA
CACAGAAATTAGCAAGCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (276-373)

• Peptidase family M50 (Peptidase_M50) (221-375)

• Trypsin-like peptidase domain (Trypsin_2) (88-234)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	52.394	93.668	0.491
htrA	Streptococcus gordonii str. Challis substr. CH1	48.285	100	0.483
htrA	Streptococcus pneumoniae D39	52.924	90.237	0.478
htrA	Streptococcus pneumoniae TIGR4	52.924	90.237	0.478
htrA	Streptococcus pneumoniae R6	52.924	90.237	0.478
htrA	Streptococcus pneumoniae Rx1	52.924	90.237	0.478
htrA	Streptococcus mutans UA159	52.819	88.918	0.47