Detailed information NTG1062365

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACF0HZ_RS08570
• Genome accession: NZ_CP171619
• Coordinates: 1693448..1695595 (+)
• Length: 715 a.a.
• NCBI ID: WP_394455401.1
• Uniprot ID: -
• Organism: Leuconostoc suionicum strain VITA-PB2
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1688448..1700595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF0HZ_RS08530 (ACF0HZ_08540)	-	1689075..1690055 (+)	981	WP_336197753.1	sensor histidine kinase	-
ACF0HZ_RS08535 (ACF0HZ_08545)	-	1690061..1690786 (+)	726	WP_072612886.1	response regulator transcription factor	-
ACF0HZ_RS08540 (ACF0HZ_08550)	-	1691058..1691435 (-)	378	WP_394455395.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08545 (ACF0HZ_08555)	-	1691720..1691896 (-)	177	WP_336197750.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08550 (ACF0HZ_08560)	-	1692058..1692237 (-)	180	WP_394455397.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08555 (ACF0HZ_08565)	-	1692252..1692389 (-)	138	WP_336197749.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08560 (ACF0HZ_08575)	-	1692848..1693009 (-)	162	WP_394455399.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08565 (ACF0HZ_08580)	-	1693039..1693215 (-)	177	WP_010287032.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACF0HZ_RS08570 (ACF0HZ_08585)	comA	1693448..1695595 (+)	2148	WP_394455401.1	peptide cleavage/export ABC transporter	Regulator
ACF0HZ_RS08575 (ACF0HZ_08590)	-	1695613..1696962 (+)	1350	WP_394455403.1	bacteriocin secretion accessory protein	-
ACF0HZ_RS08580 (ACF0HZ_08595)	-	1697781..1697906 (-)	126	WP_011679061.1	putative metal homeostasis protein	-
ACF0HZ_RS08585 (ACF0HZ_08600)	-	1698022..1698759 (-)	738	WP_394455406.1	SDR family NAD(P)-dependent oxidoreductase	-
ACF0HZ_RS08590 (ACF0HZ_08605)	-	1698817..1699404 (-)	588	WP_394455408.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80318.21 Da
• Isoelectric Point: 9.1333

>NTDB_id=1062365 ACF0HZ_RS08570 WP_394455401.1 1693448..1695595(+) (comA) [Leuconostoc suionicum strain VITA-PB2]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFEMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVGKTAMTLQEFSKEWTGVALFMSPSPKYKPFKENKNSILSFLPIIS
RQKGLIANIVAASLLVTLISIAGSYYMQLVIDAYIPSAMSNTLTVVSLGLITTYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKRSFAHQKSEAIQNSIKQATQLII
NVLILWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NITVDDVSYQYGYQKNILHHFSIKIPFGEKVALVGVSGSGKSTLAKLLVNFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=1062365 ACF0HZ_RS08570 WP_394455401.1 1693448..1695595(+) (comA) [Leuconostoc suionicum strain VITA-PB2]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGCGAACGCTGTCAAACATCTTTATCAGGTACAACGGCGTTAGGCTTAGTGA
AAGCCGCTGAATCATTTAATATGGATGTCCGTCCAATTCAAGCTGACTTGACTTTGTTCGAAATGAAAGATTTACCTCTG
CCGTTTATCGCTCATGTTGAGAAAAAAGGTCAATACTTACATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
TATTGCAGATCCAGATCCAACAGTTGGTAAAACCGCAATGACGTTACAGGAATTCTCCAAAGAGTGGACTGGGGTAGCAT
TGTTCATGTCGCCTTCACCCAAATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTTTACCAATTATTAGC
CGACAAAAAGGATTAATTGCTAATATTGTCGCCGCTTCTTTGCTAGTCACCTTAATTAGTATCGCTGGTTCTTATTACAT
GCAACTAGTGATCGATGCCTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGGCTCATTACCACCT
ATGTGTTACAACAACTACTTAGTTTTGCTCGAACCTATTTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGTCACTTGTTCGAACTGCCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTAACGCGTTT
TAATGACGCCAATACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGTAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTACTATCTCTAATCTCTTTCCCTATCTACTTCTTGATTGTC
TACTGTTTCATGAAACCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACACTTAGCTCCTCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACAAGCTATCAAAAAATTGATCGTGAATTTGTTG
ATTATTTAAAAAGGTCCTTTGCCCACCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTACTCATTTTATGGTTGGGCGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACTTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAATTTAAAAAATCAGAATCACAAGAGCTTCATCATAATAACCCTCAT
AATATTACAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATTCCCTT
TGGTGAAAAAGTTGCTCTGGTCGGTGTTAGTGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTAATTTTATATCAC
CTAGTGCTGGAAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGCCAAAATTTAAGACAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAACTTAACACTAGGTGCTCGTGAAAATACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGACGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
GACAATCATTTTTATTGCACATCGCCTGACCATTGCTGAAAAAGTCCAACGTGTTATTCTACTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-436)

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.804	99.86	0.597
comA	Streptococcus mitis NCTC 12261	58.567	99.58	0.583
comA	Streptococcus mitis SK321	58.287	99.58	0.58
comA	Streptococcus pneumoniae D39	58.006	99.58	0.578
comA	Streptococcus pneumoniae Rx1	58.006	99.58	0.578
comA	Streptococcus pneumoniae R6	58.006	99.58	0.578
comA	Streptococcus pneumoniae TIGR4	57.725	99.58	0.575
comA/nlmT	Streptococcus mutans UA159	54.571	99.441	0.543