Detailed information NTG1059283

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ACFKHK_RS09680
• Genome accession: NZ_CP170760
• Coordinates: 1841732..1842415 (+)
• Length: 227 a.a.
• NCBI ID: WP_174846438.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain FZ2
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1833257..1842415	1841732..1842415	within	0

Gene organization within MGE regions

Location: 1833257..1842415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFKHK_RS09635	-	1833257..1835017 (-)	1761	WP_392462027.1	glycerophosphodiester phosphodiesterase	-
ACFKHK_RS09640	-	1835097..1835711 (+)	615	WP_392462029.1	GNAT family N-acetyltransferase	-
ACFKHK_RS09645	-	1836041..1836535 (-)	495	WP_172036914.1	DUF536 domain-containing protein	-
ACFKHK_RS09650	-	1836885..1837979 (-)	1095	Protein_1872	IS3 family transposase	-
ACFKHK_RS09655	-	1838060..1839502 (-)	1443	WP_174846724.1	multicopper oxidase family protein	-
ACFKHK_RS09660	-	1839650..1840794 (+)	1145	WP_392462031.1	IS3 family transposase	-
ACFKHK_RS09665	-	1840997..1841131 (-)	135	Protein_1875	IS256 family transposase	-
ACFKHK_RS09670	-	1841393..1841554 (+)	162	Protein_1876	multicopper oxidase domain-containing protein	-
ACFKHK_RS09675	-	1841634..1841696 (+)	63	WP_253952881.1	multicopper oxidase domain-containing protein	-
ACFKHK_RS09680	vicR	1841732..1842415 (+)	684	WP_174846438.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 227 a.a.
• Molecular weight: 25694.80 Da
• Isoelectric Point: 5.0348

>NTDB_id=1059283 ACFKHK_RS09680 WP_174846438.1 1841732..1842415(+) (vicR) [Streptococcus parasuis strain FZ2]
MKILIVDDEASILNIVEAYLSAKGYQVFRALSGNEALTKVDVVQPDLIVLDLMLPGLSGLEVCKKIRDSSTVPIIMLTAK
TAEKDILEGLSLGADDYITKPFSPKELVARVETVLRRVQPEYREEKWSFEEGLLVIYPDRKQVFKRGEEIILTPTEYALL
ALLASHPMRLFSREQLLDAVKGLDFDGTDRVIDTHIKNIRQKIEDDTRNPYFILTAYGMGYRFGGQK

Nucleotide

• Length: 684 bp

>NTDB_id=1059283 ACFKHK_RS09680 WP_174846438.1 1841732..1842415(+) (vicR) [Streptococcus parasuis strain FZ2]
GTGAAGATTTTAATTGTGGACGACGAAGCAAGCATTCTGAATATCGTGGAAGCCTATTTGAGTGCAAAAGGCTATCAAGT
GTTTCGCGCTTTGAGCGGAAACGAGGCTTTAACAAAGGTTGATGTTGTCCAACCTGACTTGATTGTGTTGGATCTCATGC
TGCCTGGTTTATCTGGCCTCGAAGTCTGTAAAAAAATAAGGGACTCCTCCACTGTACCGATTATCATGTTGACTGCGAAA
ACAGCCGAAAAAGATATCTTGGAAGGGTTAAGCCTGGGGGCTGATGACTACATCACAAAACCATTCAGCCCGAAAGAGCT
GGTTGCTCGGGTCGAAACCGTTTTACGCCGTGTCCAACCAGAATACCGAGAAGAAAAGTGGTCTTTCGAAGAAGGTTTGC
TGGTTATCTACCCGGATCGAAAACAAGTATTCAAACGAGGTGAAGAAATCATTTTGACCCCGACCGAGTATGCTTTATTA
GCCCTTCTGGCCTCACATCCAATGCGCCTATTTTCACGGGAACAGCTGCTGGACGCTGTGAAAGGACTCGATTTTGATGG
AACGGATCGGGTGATCGATACCCACATCAAAAATATCCGTCAAAAAATTGAGGACGACACGCGCAACCCCTACTTCATCT
TAACCGCATATGGAATGGGGTATCGATTTGGTGGTCAAAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-223)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	48.458	100	0.485
micA	Streptococcus pneumoniae Cp1015	48.23	99.559	0.48
scnR	Streptococcus mutans UA159	37.826	100	0.383
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.839	98.678	0.383
covR	Streptococcus salivarius strain HSISS4	38.393	98.678	0.379