Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFKHK_RS08740 Genome accession   NZ_CP170760
Coordinates   1663566..1664282 (-) Length   238 a.a.
NCBI ID   WP_174845639.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1658566..1669282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS08720 - 1658930..1660156 (-) 1227 WP_392461877.1 cysteine desulfurase -
  ACFKHK_RS08725 sufD 1660161..1661423 (-) 1263 WP_312248278.1 Fe-S cluster assembly protein SufD -
  ACFKHK_RS08730 sufC 1661440..1662213 (-) 774 WP_312249330.1 Fe-S cluster assembly ATPase SufC -
  ACFKHK_RS08735 - 1662385..1663569 (-) 1185 WP_392461880.1 glycosyltransferase family 4 protein -
  ACFKHK_RS08740 mecA 1663566..1664282 (-) 717 WP_174845639.1 adaptor protein MecA Regulator
  ACFKHK_RS08745 - 1664488..1665327 (-) 840 WP_174845662.1 undecaprenyl-diphosphate phosphatase -
  ACFKHK_RS08750 - 1665602..1667164 (+) 1563 WP_392461882.1 ABC transporter substrate-binding protein/permease -
  ACFKHK_RS08755 - 1667157..1667900 (+) 744 WP_392461884.1 amino acid ABC transporter ATP-binding protein -
  ACFKHK_RS08760 - 1668009..1668218 (-) 210 WP_024391394.1 hypothetical protein -
  ACFKHK_RS08765 - 1668308..1669210 (-) 903 WP_216806428.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27865.52 Da        Isoelectric Point: 4.1340

>NTDB_id=1059280 ACFKHK_RS08740 WP_174845639.1 1663566..1664282(-) (mecA) [Streptococcus parasuis strain FZ2]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSTHDSKAVRQLEDAEKEDSDEYQEPYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTV

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1059280 ACFKHK_RS08740 WP_174845639.1 1663566..1664282(-) (mecA) [Streptococcus parasuis strain FZ2]
ATGAAAGTAAAACAAATAAGTGATTCGACTCTAAAAATCACTATCCAATTAGAGGATTTAGAGGAGCGCGGGATGGAAAT
TGCGGATTTCCTTATCCCTCAAGAAAAGACGGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTGGAACGTACAGTTCGTGAACGAAGCACGCATGACTCAAAAGCAGTTCGTCAATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACCGTATATTTACTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAAGTGGAGCAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCGGAGTATATTCTATCTCGCATGCTTGAATTTACAAACGATACCAAATTGACACGAC
CATTTCTTCAAGAGCACGGAATCTTGATGTTGGGAAATGGGGCCATTGATGAGTTGAAAAAGGTGCAAACGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.508
  mecA Streptococcus pneumoniae D39

49.59

100

0.508
  mecA Streptococcus pneumoniae R6

49.59

100

0.508
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.508
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

45.714

100

0.471
  mecA Streptococcus thermophilus LMG 18311

45.306

100

0.466

Multiple sequence alignment