Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFKHJ_RS08730 Genome accession   NZ_CP170759
Coordinates   1685289..1686005 (-) Length   238 a.a.
NCBI ID   WP_174845639.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1680289..1691005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHJ_RS08710 - 1680653..1681879 (-) 1227 WP_392452507.1 cysteine desulfurase -
  ACFKHJ_RS08715 sufD 1681884..1683146 (-) 1263 WP_239604208.1 Fe-S cluster assembly protein SufD -
  ACFKHJ_RS08720 sufC 1683163..1683936 (-) 774 WP_171989104.1 Fe-S cluster assembly ATPase SufC -
  ACFKHJ_RS08725 - 1684108..1685292 (-) 1185 WP_392452509.1 glycosyltransferase family 4 protein -
  ACFKHJ_RS08730 mecA 1685289..1686005 (-) 717 WP_174845639.1 adaptor protein MecA Regulator
  ACFKHJ_RS08735 - 1686211..1687050 (-) 840 WP_171989131.1 undecaprenyl-diphosphate phosphatase -
  ACFKHJ_RS08740 - 1687314..1688876 (+) 1563 WP_392452511.1 ABC transporter substrate-binding protein/permease -
  ACFKHJ_RS08745 - 1688869..1689612 (+) 744 WP_172024814.1 amino acid ABC transporter ATP-binding protein -
  ACFKHJ_RS08750 - 1689721..1689930 (-) 210 WP_024391394.1 hypothetical protein -
  ACFKHJ_RS08755 - 1690020..1690922 (-) 903 WP_216806428.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27865.52 Da        Isoelectric Point: 4.1340

>NTDB_id=1059224 ACFKHJ_RS08730 WP_174845639.1 1685289..1686005(-) (mecA) [Streptococcus parasuis strain FZ1]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSTHDSKAVRQLEDAEKEDSDEYQEPYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTV

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1059224 ACFKHJ_RS08730 WP_174845639.1 1685289..1686005(-) (mecA) [Streptococcus parasuis strain FZ1]
ATGAAAGTAAAACAAATAAGTGATTCGACTCTAAAAATCACTATCCAATTAGAAGATTTAGAGGAGCGCGGGATGGAAAT
TGCAGATTTCCTTATCCCTCAAGAAAAGACGGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTGGAACGTACAGTTCGTGAACGAAGCACGCATGACTCAAAAGCAGTTCGTCAATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACCGTATATTTACTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAGGTGGAACAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCGGAGTATATTCTATCTCGCATGCTTGAATTTACAAACGATACCAAATTGACACGAC
CATTTCTTCAAGAGCACGGAATCTTGATGTTGGGAAATGGGGCCATTGATGAGTTGAAAAAGGTGCAAACGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.508
  mecA Streptococcus pneumoniae D39

49.59

100

0.508
  mecA Streptococcus pneumoniae R6

49.59

100

0.508
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.508
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

45.714

100

0.471
  mecA Streptococcus thermophilus LMG 18311

45.306

100

0.466

Multiple sequence alignment