Detailed information NTG0105916

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AABA08_RS09355
• Genome accession: NZ_AP028602
• Coordinates: 1826298..1826759 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PF2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1821298..1831759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA08_RS09320 (TKY092604_18130)	-	1821603..1822427 (-)	825	WP_000727909.1	membrane protein insertase YidC	-
AABA08_RS09325 (TKY092604_18140)	rnpA	1822402..1822773 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AABA08_RS09330	-	1822790..1822921 (-)	132	WP_000768904.1	hypothetical protein	-
AABA08_RS09335 (TKY092604_18150)	-	1822922..1824112 (-)	1191	WP_000167769.1	acetate kinase	-
AABA08_RS09340 (TKY092604_18160)	comYH	1824163..1825116 (-)	954	WP_000345080.1	class I SAM-dependent methyltransferase	Machinery gene
AABA08_RS09345	-	1825177..1825771 (-)	595	Protein_1816	class I SAM-dependent methyltransferase	-
AABA08_RS09350 (TKY092604_18190)	comGG/cglG	1825874..1826320 (-)	447	WP_001842224.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABA08_RS09355	comGF/cglF	1826298..1826759 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABA08_RS09360 (TKY092604_18210)	comGE/cglE	1826722..1827024 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABA08_RS09365 (TKY092604_18220)	comGD/cglD	1826987..1827391 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABA08_RS09370 (TKY092604_18230)	comGC/cglC	1827384..1827710 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
AABA08_RS09375 (TKY092604_18240)	comGB/cglB	1827712..1828728 (-)	1017	WP_078102766.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABA08_RS09380 (TKY092604_18250)	comGA/cglA/cilD	1828676..1829617 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
AABA08_RS09385 (TKY092604_18260)	-	1829693..1830058 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABA08_RS09390 (TKY092604_18270)	-	1830209..1831267 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=105916 AABA08_RS09355 WP_000250539.1 1826298..1826759(-) (comGF/cglF) [Streptococcus pneumoniae strain PF2]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=105916 AABA08_RS09355 WP_000250539.1 1826298..1826759(-) (comGF/cglF) [Streptococcus pneumoniae strain PF2]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915