Detailed information    

insolico Bioinformatically predicted

Overview


Name   comA   Type   Regulator
Locus tag   ACFLK2_RS04045 Genome accession   NZ_CP170617
Coordinates   705012..705185 (+) Length   57 a.a.
NCBI ID   WP_004996409.1    Uniprot ID   Q7PB38
Organism   Rickettsia sibirica strain MT84     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 700012..710185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFLK2_RS04025 (ACFLK2_04025) thrS 701200..703107 (+) 1908 WP_004996417.1 threonine--tRNA ligase -
  ACFLK2_RS04030 (ACFLK2_04030) - 703195..703419 (+) 225 WP_004996414.1 hypothetical protein -
  ACFLK2_RS04035 (ACFLK2_04035) - 703672..704271 (+) 600 WP_004996413.1 hypothetical protein -
  ACFLK2_RS04040 (ACFLK2_04040) - 704757..704846 (+) 90 WP_162009633.1 ATP-binding cassette domain-containing protein -
  ACFLK2_RS04045 (ACFLK2_04045) comA 705012..705185 (+) 174 WP_004996409.1 ATP-binding cassette domain-containing protein Regulator
  ACFLK2_RS04050 (ACFLK2_04050) comA/nlmT 705210..705365 (+) 156 WP_004996407.1 hypothetical protein Regulator
  ACFLK2_RS04055 (ACFLK2_04055) - 705414..705671 (-) 258 WP_004996405.1 DUF2310 family Zn-ribbon-containing protein -
  ACFLK2_RS04060 (ACFLK2_04060) - 705680..706051 (-) 372 WP_004996402.1 DUF2310 family Zn-ribbon-containing protein -
  ACFLK2_RS04065 (ACFLK2_04065) - 706400..706816 (-) 417 WP_004996401.1 DUF2660 domain-containing protein -
  ACFLK2_RS04070 (ACFLK2_04070) - 707013..707495 (-) 483 WP_016728142.1 hypothetical protein -
  ACFLK2_RS04075 (ACFLK2_04075) - 707703..707903 (-) 201 WP_032849764.1 hypothetical protein -
  ACFLK2_RS04080 (ACFLK2_04080) - 708212..709573 (+) 1362 WP_004996393.1 TolC family outer membrane protein -
  ACFLK2_RS04085 (ACFLK2_04085) - 709575..709973 (+) 399 WP_010976966.1 DUF2497 domain-containing protein -

Sequence


Protein


Download         Length: 57 a.a.        Molecular weight: 6232.25 Da        Isoelectric Point: 10.4654

>NTDB_id=1058182 ACFLK2_RS04045 WP_004996409.1 705012..705185(+) (comA) [Rickettsia sibirica strain MT84]
MNLSKVYRKNINTIVGERGVKLSGGQRQRIAIVLAILKNAPILVLDEATSSLDSHTE

Nucleotide


Download         Length: 174 bp        

>NTDB_id=1058182 ACFLK2_RS04045 WP_004996409.1 705012..705185(+) (comA) [Rickettsia sibirica strain MT84]
ATGAATTTATCGAAAGTTTACCGGAAAAATATAAACACCATTGTCGGTGAGAGAGGAGTAAAGCTAAGTGGTGGACAGAG
GCAACGTATAGCAATTGTCCTTGCTATTCTTAAAAACGCTCCGATTTTGGTTTTAGATGAAGCAACTTCAAGCCTTGATA
GCCATACAGAGTAA

Domains


Predicted by InterproScan.

(10-50)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q7PB38

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

60.417

84.211

0.509

  comA Streptococcus gordonii str. Challis substr. CH1

58.333

84.211

0.491

  comA Streptococcus pneumoniae TIGR4

58.333

84.211

0.491

  comA Streptococcus mitis NCTC 12261

58.333

84.211

0.491

  comA Streptococcus pneumoniae Rx1

58.333

84.211

0.491

  comA Streptococcus pneumoniae R6

58.333

84.211

0.491

  comA Streptococcus pneumoniae D39

58.333

84.211

0.491

  rcrQ Streptococcus mutans UA159

49.057

92.982

0.456

  comA/nlmT Streptococcus mutans UA159

64.103

68.421

0.439

  rcrP Streptococcus mutans UA159

37.5

98.246

0.368


Multiple sequence alignment