Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   DK93_RS00665 Genome accession   NZ_CP007562
Coordinates   104364..104792 (+) Length   142 a.a.
NCBI ID   WP_023605232.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS327     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99364..109792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK93_RS00645 (DK93_00660) - 101694..102059 (+) 366 WP_002986560.1 DUF1033 family protein -
  DK93_RS00650 (DK93_00665) comGA 102152..103090 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  DK93_RS00655 (DK93_00670) comGB 103026..104061 (+) 1036 Protein_83 competence type IV pilus assembly protein ComGB -
  DK93_RS00660 (DK93_00675) comGC 104063..104389 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DK93_RS00665 (DK93_00680) comGD 104364..104792 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK93_RS00670 (DK93_00685) comGE 104749..105033 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK93_RS00675 (DK93_00690) comGF 105026..105460 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK93_RS00680 (DK93_00695) comGG 105444..105770 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  DK93_RS00685 (DK93_00700) comGH 105868..106821 (+) 954 WP_023610092.1 class I SAM-dependent methyltransferase Machinery gene
  DK93_RS00690 (DK93_00705) - 106880..108076 (+) 1197 WP_038431193.1 acetate kinase -
  DK93_RS00695 (DK93_00710) - 108263..108571 (+) 309 WP_032467031.1 hypothetical protein -
  DK93_RS00700 (DK93_00715) proC 108654..109424 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16256.99 Da        Isoelectric Point: 10.1022

>NTDB_id=105680 DK93_RS00665 WP_023605232.1 104364..104792(+) (comGD) [Streptococcus pyogenes strain NGAS327]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRCFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=105680 DK93_RS00665 WP_023605232.1 104364..104792(+) (comGD) [Streptococcus pyogenes strain NGAS327]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGATGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

44.961

90.845

0.408
  comGD Streptococcus mutans UA159

44.961

90.845

0.408
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366