Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACEY2C_RS12860 Genome accession   NZ_CP169314
Coordinates   2671046..2672353 (-) Length   435 a.a.
NCBI ID   WP_005470737.1    Uniprot ID   A0A6I4XEG1
Organism   Enterococcus gallinarum strain IFEGHNEK1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2666046..2677353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEY2C_RS12830 (ACEY2C_12830) - 2666387..2667430 (+) 1044 WP_003125821.1 hypothetical protein -
  ACEY2C_RS12835 (ACEY2C_12835) - 2667548..2667892 (-) 345 WP_003125823.1 PepSY domain-containing protein -
  ACEY2C_RS12840 (ACEY2C_12840) pepA 2668086..2669162 (+) 1077 WP_040013655.1 glutamyl aminopeptidase -
  ACEY2C_RS12845 (ACEY2C_12845) - 2669380..2669694 (+) 315 WP_003125825.1 thioredoxin family protein -
  ACEY2C_RS12850 (ACEY2C_12850) - 2669713..2670168 (+) 456 WP_005470736.1 universal stress protein -
  ACEY2C_RS12855 (ACEY2C_12855) ytpR 2670380..2670991 (+) 612 WP_003125829.1 YtpR family tRNA-binding protein -
  ACEY2C_RS12860 (ACEY2C_12860) htrA 2671046..2672353 (-) 1308 WP_005470737.1 S1C family serine protease Regulator
  ACEY2C_RS12865 (ACEY2C_12865) rlmH 2672633..2673112 (+) 480 WP_003125832.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACEY2C_RS12870 (ACEY2C_12870) - 2673161..2674009 (+) 849 WP_003125833.1 hypothetical protein -
  ACEY2C_RS12875 (ACEY2C_12875) - 2674292..2675113 (-) 822 WP_142434549.1 MurR/RpiR family transcriptional regulator -
  ACEY2C_RS12880 (ACEY2C_12880) - 2675238..2676314 (+) 1077 WP_003125835.1 PTS transporter subunit EIIC -
  ACEY2C_RS12885 (ACEY2C_12885) - 2676307..2677110 (+) 804 WP_374848647.1 glucose PTS transporter subunit IIA -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 44865.73 Da        Isoelectric Point: 4.3788

>NTDB_id=1050446 ACEY2C_RS12860 WP_005470737.1 2671046..2672353(-) (htrA) [Enterococcus gallinarum strain IFEGHNEK1]
MVRKNVTPGRKPSSGLLKKLGIGILGGVVGGLLTFGGLYLAMGSSLTSPVTTATSGVQDNNGQTKVSNVKYDVNSDVTKA
VEKVQGAVVSIINLQQNNANGLEGLFGSGQQGGQGSGTENSGDDSSLEASSEGSGVIYKVDGDKAYIVTNNHVVEGQDGL
EVVLSDGTKVKAELVGTDAYTDLAVLRISSDKVDTVASFGDSDSLKVGEPAIAIGSPLGSSFANSVTQGIVSSLNRQVTN
QNESGEAVSINAIQTDAAINPGNSGGPLINVEGQVIGINSSKIASTSESTSSVSVEGMGFAIPSNDVVDIINQLEKDGKV
VRPALGIRTINLSSITSQQQEQILKVPSSVTDGVVVYSVNNATPAEQAGLKQYDVITKIDDTDISTTTDLQSALYKHKVG
DTITVTFYRGKEEKTAKVVLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=1050446 ACEY2C_RS12860 WP_005470737.1 2671046..2672353(-) (htrA) [Enterococcus gallinarum strain IFEGHNEK1]
ATGGTACGAAAAAATGTGACACCAGGAAGAAAACCTTCTTCCGGCTTATTAAAAAAATTAGGTATTGGCATTCTTGGCGG
AGTAGTTGGTGGTTTGTTGACCTTCGGCGGACTTTATCTGGCGATGGGCTCTTCTTTGACTTCACCTGTAACGACCGCAA
CCAGCGGTGTTCAAGATAACAATGGACAAACGAAAGTCTCCAATGTTAAATATGACGTCAACAGCGATGTAACAAAAGCA
GTCGAAAAAGTGCAAGGAGCAGTCGTTTCGATCATCAACTTGCAACAAAATAATGCGAATGGCCTCGAAGGGTTATTTGG
CTCTGGTCAGCAAGGTGGTCAAGGATCAGGGACTGAGAATTCAGGCGATGACAGTTCACTAGAAGCTTCTTCTGAAGGAA
GTGGCGTGATTTATAAAGTAGATGGTGACAAAGCGTATATCGTTACGAATAACCACGTAGTAGAAGGACAAGATGGTTTG
GAAGTCGTTCTCTCTGATGGCACAAAAGTCAAAGCTGAATTAGTCGGAACAGACGCTTACACTGACCTTGCTGTTTTACG
CATCTCTTCTGATAAAGTAGACACGGTTGCTTCTTTCGGCGATTCTGATTCACTAAAAGTTGGCGAACCAGCAATTGCGA
TTGGTTCTCCATTAGGATCTAGCTTTGCAAATTCTGTAACGCAAGGGATTGTTTCTTCTCTGAATCGTCAAGTAACGAAT
CAAAATGAATCTGGTGAAGCAGTCAGCATCAATGCGATTCAAACAGATGCAGCGATCAACCCAGGAAACTCTGGTGGTCC
ACTGATCAACGTTGAAGGACAAGTGATCGGAATCAACTCTAGCAAGATCGCCAGCACTTCTGAATCAACATCAAGTGTCA
GCGTAGAAGGAATGGGCTTCGCGATCCCAAGTAACGACGTTGTCGATATTATCAACCAATTAGAAAAAGACGGCAAAGTT
GTTCGTCCAGCATTGGGTATTCGAACAATCAACTTAAGCTCAATCACTTCGCAACAACAAGAACAAATCTTGAAAGTACC
ATCTTCTGTCACTGACGGAGTAGTCGTATACTCAGTAAATAACGCGACACCAGCTGAACAAGCAGGATTGAAACAATACG
ATGTCATCACGAAAATCGATGATACCGACATCAGCACAACCACAGATCTACAATCTGCACTGTACAAGCACAAAGTCGGT
GATACGATCACAGTGACGTTCTACCGCGGCAAAGAAGAAAAAACAGCCAAAGTCGTTCTATCTGTAGATACTTCGATCAA
TGAACAATCGACTGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(323-419)

Peptidase family M50 (Peptidase_M50)

(263-421)

Trypsin-like peptidase domain (Trypsin_2)

(133-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4XEG1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.528

91.494

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

50.827

97.241

0.494
  htrA Streptococcus mitis NCTC 12261

54.377

86.667

0.471
  htrA Streptococcus pneumoniae TIGR4

55.682

80.92

0.451
  htrA Streptococcus pneumoniae Rx1

55.682

80.92

0.451
  htrA Streptococcus pneumoniae D39

55.682

80.92

0.451
  htrA Streptococcus pneumoniae R6

55.682

80.92

0.451

Multiple sequence alignment