Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACETQL_RS08875 Genome accession   NZ_CP169064
Coordinates   1861009..1863201 (-) Length   730 a.a.
NCBI ID   WP_003585566.1    Uniprot ID   A0A829GXH9
Organism   Lacticaseibacillus paracasei strain FMT2     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1856009..1868201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACETQL_RS08845 (ACETQL_08845) - 1856175..1856459 (-) 285 WP_003567331.1 bacteriocin immunity protein -
  ACETQL_RS08850 (ACETQL_08850) - 1856652..1856948 (-) 297 WP_003596056.1 bacteriocin immunity protein -
  ACETQL_RS08855 (ACETQL_08855) - 1857050..1858405 (-) 1356 WP_003567335.1 threonine/serine exporter ThrE family protein -
  ACETQL_RS08860 (ACETQL_08860) - 1858711..1859022 (-) 312 WP_003580849.1 hypothetical protein -
  ACETQL_RS08865 (ACETQL_08865) - 1859095..1859445 (-) 351 WP_003567340.1 hypothetical protein -
  ACETQL_RS08870 (ACETQL_08870) - 1859619..1860998 (-) 1380 WP_003585563.1 bacteriocin secretion accessory protein -
  ACETQL_RS08875 (ACETQL_08875) comA 1861009..1863201 (-) 2193 WP_003585566.1 peptide cleavage/export ABC transporter Regulator
  ACETQL_RS08880 (ACETQL_08880) - 1863667..1863804 (-) 138 WP_003571414.1 bacteriocin-like peptide, LSEI_2386 family -
  ACETQL_RS08885 (ACETQL_08885) - 1863994..1865292 (+) 1299 WP_003580853.1 GHKL domain-containing protein -
  ACETQL_RS08890 (ACETQL_08890) - 1865297..1866104 (+) 808 Protein_1719 LytR/AlgR family response regulator transcription factor -
  ACETQL_RS08895 (ACETQL_08895) - 1866466..1866663 (-) 198 WP_016383118.1 hypothetical protein -
  ACETQL_RS08900 (ACETQL_08900) - 1867210..1867479 (+) 270 WP_016369462.1 hypothetical protein -
  ACETQL_RS08905 (ACETQL_08905) - 1867723..1867896 (-) 174 WP_013246049.1 bacteriocin -
  ACETQL_RS08910 (ACETQL_08910) - 1867935..1868108 (-) 174 WP_373443355.1 hypothetical protein -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81282.51 Da        Isoelectric Point: 7.0227

>NTDB_id=1049678 ACETQL_RS08875 WP_003585566.1 1861009..1863201(-) (comA) [Lacticaseibacillus paracasei strain FMT2]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=1049678 ACETQL_RS08875 WP_003585566.1 1861009..1863201(-) (comA) [Lacticaseibacillus paracasei strain FMT2]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGTTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGGACGACGGCATTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCGGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATTACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATATTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGACTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGCGGATCAGGAAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACAGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(510-662)

Peptidase C39 family (Peptidase_C39)

(16-152)

ABC transporter transmembrane region (ABC_membrane)

(180-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A829GXH9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

59.053

98.356

0.581
  comA Streptococcus pneumoniae Rx1

58.496

98.356

0.575
  comA Streptococcus pneumoniae D39

58.496

98.356

0.575
  comA Streptococcus pneumoniae R6

58.496

98.356

0.575
  comA Streptococcus mitis SK321

58.357

98.356

0.574
  comA Streptococcus pneumoniae TIGR4

58.078

98.356

0.571
  comA Streptococcus gordonii str. Challis substr. CH1

57.103

98.356

0.562
  comA/nlmT Streptococcus mutans UA159

54.986

98.904

0.544

Multiple sequence alignment