Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACD268_RS11370 Genome accession   NZ_CP168299
Coordinates   2187205..2187867 (-) Length   220 a.a.
NCBI ID   WP_330773538.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2182205..2192867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS11345 (ACD268_11345) - 2182355..2182621 (-) 267 WP_001278167.1 Veg family protein -
  ACD268_RS11350 (ACD268_11350) dnaB 2182623..2183975 (-) 1353 WP_050239244.1 replicative DNA helicase -
  ACD268_RS11355 (ACD268_11355) rplI 2184019..2184471 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  ACD268_RS11360 (ACD268_11360) - 2184468..2186441 (-) 1974 WP_000715106.1 DHH family phosphoesterase -
  ACD268_RS11365 (ACD268_11365) hpf 2186577..2187110 (-) 534 WP_373382347.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACD268_RS11370 (ACD268_11370) comFC/cflB 2187205..2187867 (-) 663 WP_330773538.1 ComF family protein Machinery gene
  ACD268_RS11375 (ACD268_11375) comFA/cflA 2187864..2189162 (-) 1299 WP_044813853.1 DEAD/DEAH box helicase Machinery gene
  ACD268_RS11380 (ACD268_11380) - 2189218..2189853 (+) 636 WP_000395738.1 YigZ family protein -
  ACD268_RS11385 (ACD268_11385) cysK 2190138..2191058 (+) 921 WP_000029867.1 cysteine synthase A -
  ACD268_RS11390 (ACD268_11390) - 2191133..2191671 (-) 539 Protein_2206 transposase -
  ACD268_RS11395 (ACD268_11395) - 2191644..2191952 (+) 309 Protein_2207 transposase -
  ACD268_RS11400 (ACD268_11400) tnpB 2192107..2192322 (-) 216 WP_232036049.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25313.16 Da        Isoelectric Point: 6.8162

>NTDB_id=1043760 ACD268_RS11370 WP_330773538.1 2187205..2187867(-) (comFC/cflB) [Streptococcus pneumoniae strain FC1]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIEEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1043760 ACD268_RS11370 WP_330773538.1 2187205..2187867(-) (comFC/cflB) [Streptococcus pneumoniae strain FC1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGAGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CGACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment