Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACD268_RS11375 Genome accession   NZ_CP168299
Coordinates   2187864..2189162 (-) Length   432 a.a.
NCBI ID   WP_044813853.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2182864..2194162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS11355 (ACD268_11355) rplI 2184019..2184471 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  ACD268_RS11360 (ACD268_11360) - 2184468..2186441 (-) 1974 WP_000715106.1 DHH family phosphoesterase -
  ACD268_RS11365 (ACD268_11365) hpf 2186577..2187110 (-) 534 WP_373382347.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACD268_RS11370 (ACD268_11370) comFC/cflB 2187205..2187867 (-) 663 WP_330773538.1 ComF family protein Machinery gene
  ACD268_RS11375 (ACD268_11375) comFA/cflA 2187864..2189162 (-) 1299 WP_044813853.1 DEAD/DEAH box helicase Machinery gene
  ACD268_RS11380 (ACD268_11380) - 2189218..2189853 (+) 636 WP_000395738.1 YigZ family protein -
  ACD268_RS11385 (ACD268_11385) cysK 2190138..2191058 (+) 921 WP_000029867.1 cysteine synthase A -
  ACD268_RS11390 (ACD268_11390) - 2191133..2191671 (-) 539 Protein_2206 transposase -
  ACD268_RS11395 (ACD268_11395) - 2191644..2191952 (+) 309 Protein_2207 transposase -
  ACD268_RS11400 (ACD268_11400) tnpB 2192107..2192322 (-) 216 WP_232036049.1 IS66 family insertion sequence element accessory protein TnpB -
  ACD268_RS11405 (ACD268_11405) tsf 2192676..2193716 (-) 1041 WP_000808062.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49504.52 Da        Isoelectric Point: 8.7540

>NTDB_id=1043761 ACD268_RS11375 WP_044813853.1 2187864..2189162(-) (comFA/cflA) [Streptococcus pneumoniae strain FC1]
MKVNLDYLGRLFTENELTAEERQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLDLYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPMLYHAVKNSVKENGLRIFLTATST
NELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1043761 ACD268_RS11375 WP_044813853.1 2187864..2189162(-) (comFA/cflA) [Streptococcus pneumoniae strain FC1]
ATGAAAGTAAATTTAGATTATCTCGGTCGTTTATTTACTGAGAATGAATTAACAGCAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCAAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGATTGCT
TCAAGCAGTAGACAAGCAAAAGCCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGATCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGGATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCATGCTTTACCACGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTTCGTTTAGGAGAACTAAAAAGACTGAATTTACCGAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGACAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAGCAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAATAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

99.306

100

0.993
  comFA/cflA Streptococcus pneumoniae D39

99.306

100

0.993
  comFA/cflA Streptococcus pneumoniae R6

99.306

100

0.993
  comFA/cflA Streptococcus pneumoniae TIGR4

99.074

100

0.991
  comFA/cflA Streptococcus mitis NCTC 12261

92.824

100

0.928
  comFA/cflA Streptococcus mitis SK321

91.898

100

0.919
  comFA Lactococcus lactis subsp. cremoris KW2

52.451

94.444

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

38.747

99.769

0.387

Multiple sequence alignment