Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACD268_RS02425 Genome accession   NZ_CP168299
Coordinates   451370..452029 (-) Length   219 a.a.
NCBI ID   WP_330789183.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 446370..457029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS02395 (ACD268_02395) - 446550..447149 (+) 600 WP_050135957.1 phosphoribosylanthranilate isomerase -
  ACD268_RS02400 (ACD268_02400) trpB 447127..448350 (+) 1224 WP_373381854.1 tryptophan synthase subunit beta -
  ACD268_RS02405 (ACD268_02405) trpA 448343..449119 (+) 777 WP_050234345.1 tryptophan synthase subunit alpha -
  ACD268_RS02410 (ACD268_02410) - 449091..449201 (-) 111 Protein_474 prepilin peptidase -
  ACD268_RS02415 (ACD268_02415) - 449421..450152 (+) 732 WP_000934017.1 hypothetical protein -
  ACD268_RS02420 (ACD268_02420) - 450167..451318 (+) 1152 WP_044813288.1 XRE family transcriptional regulator -
  ACD268_RS02425 (ACD268_02425) cclA/cilC 451370..452029 (-) 660 WP_330789183.1 A24 family peptidase Machinery gene
  ACD268_RS02430 (ACD268_02430) - 452099..452545 (+) 447 WP_050281115.1 GNAT family N-acetyltransferase -
  ACD268_RS02435 (ACD268_02435) - 452773..453951 (-) 1179 WP_050220746.1 ROK family transcriptional regulator -
  ACD268_RS02440 (ACD268_02440) - 454231..455493 (+) 1263 WP_000413347.1 PTS sugar transporter subunit IIC -
  ACD268_RS02445 (ACD268_02445) - 455496..456392 (+) 897 WP_000825664.1 PEP phosphonomutase -
  ACD268_RS02450 (ACD268_02450) - 456407..456724 (+) 318 WP_044791088.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24834.95 Da        Isoelectric Point: 7.2761

>NTDB_id=1043700 ACD268_RS02425 WP_330789183.1 451370..452029(-) (cclA/cilC) [Streptococcus pneumoniae strain FC1]
MIDFYFFLIGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1043700 ACD268_RS02425 WP_330789183.1 451370..452029(-) (cclA/cilC) [Streptococcus pneumoniae strain FC1]
ATGATTGATTTTTATTTTTTTCTCATCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCATCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

91.324

100

0.913
  cclA/cilC Streptococcus mitis NCTC 12261

86.301

100

0.863

Multiple sequence alignment