Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   QUE88_RS01765 Genome accession   NZ_AP028145
Coordinates   384118..386268 (+) Length   716 a.a.
NCBI ID   WP_063722043.1    Uniprot ID   A0A1E3KNV5
Organism   Lactiplantibacillus plantarum strain IYO2065     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 379118..391268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE88_RS01730 (IYO2065_03510) - 379197..379943 (+) 747 WP_003643806.1 CPBP family intramembrane glutamic endopeptidase -
  QUE88_RS01735 (IYO2065_03520) - 380075..380224 (+) 150 WP_003643807.1 hypothetical protein -
  QUE88_RS01740 (IYO2065_03540) - 380867..381577 (+) 711 WP_286265011.1 GHKL domain-containing protein -
  QUE88_RS01745 (IYO2065_03550) - 381578..382321 (+) 744 WP_003643809.1 response regulator transcription factor -
  QUE88_RS01750 (IYO2065_03560) - 382626..383399 (-) 774 WP_003643810.1 CPBP family intramembrane glutamic endopeptidase -
  QUE88_RS01755 (IYO2065_03570) plnF 383498..383656 (-) 159 WP_003643811.1 two-peptide bacteriocin plantaricin EF subunit PlnF -
  QUE88_RS01760 (IYO2065_03580) plnE 383681..383851 (-) 171 WP_003641985.1 two-peptide bacteriocin plantaricin EF subunit PlnE -
  QUE88_RS01765 (IYO2065_03590) comA 384118..386268 (+) 2151 WP_063722043.1 peptide cleavage/export ABC transporter Regulator
  QUE88_RS01770 (IYO2065_03600) - 386284..387678 (+) 1395 WP_063722042.1 HlyD family secretion protein -
  QUE88_RS01775 (IYO2065_03610) - 387768..388457 (+) 690 WP_062688864.1 type II CAAX endopeptidase family protein -
  QUE88_RS01780 (IYO2065_03620) - 388524..389192 (+) 669 WP_063721086.1 CPBP family intramembrane glutamic endopeptidase -
  QUE88_RS01785 (IYO2065_03630) - 389279..389959 (+) 681 WP_053566440.1 CPBP family intramembrane glutamic endopeptidase -
  QUE88_RS01790 (IYO2065_03640) - 390053..390739 (+) 687 WP_053566441.1 CPBP family intramembrane glutamic endopeptidase -
  QUE88_RS01795 - 390855..391142 (+) 288 WP_063722041.1 type II toxin-antitoxin system RelE/ParE family toxin -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79924.61 Da        Isoelectric Point: 6.6531

>NTDB_id=104049 QUE88_RS01765 WP_063722043.1 384118..386268(+) (comA) [Lactiplantibacillus plantarum strain IYO2065]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFEVQDLPL
PFLAHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=104049 QUE88_RS01765 WP_063722043.1 384118..386268(+) (comA) [Lactiplantibacillus plantarum strain IYO2065]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGAGGTACAAGATTTACCATTG
CCATTCCTTGCGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTCGTTGTAAAAACCTCGAAAACACATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCAGTGGTGGCCATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCAAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAAAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAAC
CAAATAGTGGTGATGTCATATTGAACGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAAAAACAATTAATCGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(166-436)

Peptidase C39 family (Peptidase_C39)

(5-140)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E3KNV5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

59.046

99.581

0.588
  comA Streptococcus pneumoniae Rx1

58.766

99.581

0.585
  comA Streptococcus pneumoniae D39

58.766

99.581

0.585
  comA Streptococcus pneumoniae R6

58.766

99.581

0.585
  comA Streptococcus pneumoniae TIGR4

58.626

99.581

0.584
  comA Streptococcus mitis SK321

58.485

99.581

0.582
  comA Streptococcus gordonii str. Challis substr. CH1

57.103

100

0.573
  comA/nlmT Streptococcus mutans UA159

54.318

100

0.545

Multiple sequence alignment