Detailed information NTG1039147

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: CIL07_RS06580
• Genome accession: NZ_CP167253
• Coordinates: 1367897..1370089 (-)
• Length: 730 a.a.
• NCBI ID: WP_100908635.1
• Uniprot ID: A0AAP9HIX0
• Organism: Lacticaseibacillus paracasei subsp. paracasei strain NTU 101
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1362897..1375089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CIL07_RS06550 (CIL07_06550)	-	1362975..1363286 (-)	312	WP_003580849.1	hypothetical protein	-
CIL07_RS06555 (CIL07_06555)	-	1363359..1363709 (-)	351	WP_003567340.1	hypothetical protein	-
CIL07_RS06560 (CIL07_06560)	-	1363883..1364023 (-)	141	Protein_1291	bacteriocin secretion accessory protein	-
CIL07_RS06565 (CIL07_06565)	-	1364177..1365592 (+)	1416	WP_003600251.1	IS5-like element ISLca2 family transposase	-
CIL07_RS06570 (CIL07_06570)	-	1365704..1366624 (+)	921	WP_003574021.1	IS30 family transposase	-
CIL07_RS06575 (CIL07_06575)	-	1366638..1367886 (-)	1249	Protein_1294	bacteriocin secretion accessory protein	-
CIL07_RS06580 (CIL07_06580)	comA	1367897..1370089 (-)	2193	WP_100908635.1	peptide cleavage/export ABC transporter	Regulator
CIL07_RS06585 (CIL07_06585)	-	1370556..1370693 (-)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
CIL07_RS06590 (CIL07_06590)	-	1370894..1372192 (+)	1299	WP_045603255.1	GHKL domain-containing protein	-
CIL07_RS06595 (CIL07_06595)	-	1372197..1373003 (+)	807	WP_003567351.1	LytTR family DNA-binding domain-containing protein	-
CIL07_RS06600 (CIL07_06600)	-	1373335..1373586 (+)	252	WP_003586983.1	IS3 family transposase	-
CIL07_RS06605 (CIL07_06605)	-	1373640..1374482 (+)	843	WP_029327644.1	IS3 family transposase	-
CIL07_RS06610 (CIL07_06610)	-	1374599..1375050 (-)	452	Protein_1301	IS5 family transposase	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81290.50 Da
• Isoelectric Point: 7.0227

>NTDB_id=1039147 CIL07_RS06580 WP_100908635.1 1367897..1370089(-) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain NTU 101]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDSSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=1039147 CIL07_RS06580 WP_100908635.1 1367897..1370089(-) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain NTU 101]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGAGCTGCTCAGGCACTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATTCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATGCTAGCGCGACAAAAAGGAATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTCGCTTATGTGCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAACGTTTGTCGATTGATGTCATTTTGGGTTACGTCAGACACCTTTATGAATTACCTATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAAATTATTGATGCGCTGGCGAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCCGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCTATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAGCAAATCAATCTTGAAATCCCAGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCAATC
AGTGATGTTGATCTAACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCAGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCAATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTGACCATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.774	98.356	0.578
comA	Streptococcus pneumoniae Rx1	58.217	98.356	0.573
comA	Streptococcus pneumoniae D39	58.217	98.356	0.573
comA	Streptococcus pneumoniae R6	58.217	98.356	0.573
comA	Streptococcus mitis SK321	58.078	98.356	0.571
comA	Streptococcus pneumoniae TIGR4	57.799	98.356	0.568
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542