Detailed information NTG1035490

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: AB3363_RS09685
• Genome accession: NZ_CP166826
• Coordinates: 1926575..1928722 (+)
• Length: 715 a.a.
• NCBI ID: WP_370928677.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides strain yan
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1921575..1933722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3363_RS09650 (AB3363_09640)	-	1922047..1922322 (-)	276	WP_004906421.1	transposase	-
AB3363_RS09655 (AB3363_09645)	-	1922412..1923452 (+)	1041	WP_370928675.1	sensor histidine kinase	-
AB3363_RS09660 (AB3363_09650)	-	1923458..1924183 (+)	726	WP_011679068.1	response regulator transcription factor	-
AB3363_RS09665 (AB3363_09655)	-	1924455..1924667 (-)	213	WP_261648397.1	hypothetical protein	-
AB3363_RS09670 (AB3363_09660)	-	1924673..1924846 (-)	174	WP_261648396.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
AB3363_RS09675 (AB3363_09665)	-	1925529..1925693 (-)	165	WP_096638839.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
AB3363_RS09680 (AB3363_09670)	-	1925686..1925886 (-)	201	WP_370928676.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
AB3363_RS09685 (AB3363_09675)	comA	1926575..1928722 (+)	2148	WP_370928677.1	peptide cleavage/export ABC transporter	Regulator
AB3363_RS09690 (AB3363_09680)	-	1928740..1929255 (+)	516	WP_370928678.1	hypothetical protein	-
AB3363_RS09695 (AB3363_09685)	-	1929399..1930088 (+)	690	WP_370928679.1	HlyD family efflux transporter periplasmic adaptor subunit	-
AB3363_RS09700 (AB3363_09690)	-	1930904..1931029 (-)	126	WP_011679061.1	putative metal homeostasis protein	-
AB3363_RS09705 (AB3363_09695)	-	1931145..1931882 (-)	738	WP_061399584.1	SDR family NAD(P)-dependent oxidoreductase	-
AB3363_RS09710 (AB3363_09700)	-	1931940..1932527 (-)	588	WP_014324154.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80349.35 Da
• Isoelectric Point: 9.1336

>NTDB_id=1035490 AB3363_RS09685 WP_370928677.1 1926575..1928722(+) (comA) [Leuconostoc mesenteroides strain yan]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIREPCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFNMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDTYIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEVIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=1035490 AB3363_RS09685 WP_370928677.1 1926575..1928722(+) (comA) [Leuconostoc mesenteroides strain yan]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACCCTGTCAAACATCCCTATCGGGTACAACGGCGCTAGGCTTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCAACATGAAAGATTTGCCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATACTTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAATTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTCACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGCAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTGCTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGTCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGGGCTCGTGAAAACACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	60.084	99.86	0.6
comA	Streptococcus mitis NCTC 12261	58.287	99.58	0.58
comA	Streptococcus mitis SK321	58.006	99.58	0.578
comA	Streptococcus pneumoniae Rx1	57.725	99.58	0.575
comA	Streptococcus pneumoniae D39	57.725	99.58	0.575
comA	Streptococcus pneumoniae R6	57.725	99.58	0.575
comA	Streptococcus pneumoniae TIGR4	57.444	99.58	0.572
comA/nlmT	Streptococcus mutans UA159	54.149	99.441	0.538