Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AB3363_RS00885 Genome accession   NZ_CP166826
Coordinates   166040..167179 (+) Length   379 a.a.
NCBI ID   WP_014325193.1    Uniprot ID   A0A5M8XCI1
Organism   Leuconostoc mesenteroides strain yan     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 161040..172179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3363_RS00865 (AB3363_00865) yycF 161197..161904 (+) 708 WP_261650092.1 response regulator YycF -
  AB3363_RS00870 (AB3363_00870) walK 161972..163837 (+) 1866 WP_025268546.1 cell wall metabolism sensor histidine kinase WalK -
  AB3363_RS00875 (AB3363_00875) - 163827..165119 (+) 1293 WP_011680489.1 hypothetical protein -
  AB3363_RS00880 (AB3363_00880) yycI 165176..165979 (+) 804 WP_010289058.1 two-component system regulatory protein YycI -
  AB3363_RS00885 (AB3363_00885) htrA 166040..167179 (+) 1140 WP_014325193.1 S1C family serine protease Regulator
  AB3363_RS00890 (AB3363_00890) rlmH 167800..168279 (+) 480 WP_011680487.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AB3363_RS00895 (AB3363_00895) - 168373..170538 (+) 2166 WP_370928706.1 YhgE/Pip family protein -
  AB3363_RS00900 (AB3363_00900) - 170592..171044 (+) 453 WP_011680485.1 Rrf2 family transcriptional regulator -
  AB3363_RS00905 (AB3363_00905) - 171129..171794 (-) 666 WP_010285559.1 NAD(P)H-hydrate epimerase -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39210.48 Da        Isoelectric Point: 9.7777

>NTDB_id=1035471 AB3363_RS00885 WP_014325193.1 166040..167179(+) (htrA) [Leuconostoc mesenteroides strain yan]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVEATSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTSVEGMGFAIPSDQVVDIVNKLVKDGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKHSLGDTITLTYYHQDTKQTVKVKLTQKLAS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=1035471 AB3363_RS00885 WP_014325193.1 166040..167179(+) (htrA) [Leuconostoc mesenteroides strain yan]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAGCAGGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTGAGTACGACAGCAACAAGTACAAAAACGATTGCCAAGA
ATGCAACTGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTGAACTTTACTAAATCCAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACGGATGGATCGGCATTTATTGTAACGAATAATCA
CGTAATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCTACATTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAAATCGACGGCACAGACGTTACAACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAACGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGCATCATTTC
GGCCAAGAAAAGGTTAGTTGAGGCAACATCTGAAAATGGTCAAAATTATGGTGGATCCACGGTTATTCAGACGGATGCTG
CTATTAATCCTGGTAACTCAGGTGGACCATTAATCAACTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTATCA
ACATCTTCTTCTGGAACGAGCGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAGATGGTAAAGTCACACGACCAGCAATTGGCATTAGTTTGATTAATTTGTCAGAAGTAACAGCTTCTGAGCAAA
AATCAACATTGAAAATTCCAGATAGCGTTACTGGTGGTGTTGTTGTAATGAGTTTGACTAACAATGGCCCAGCAGATAAA
GCTGGATTGAAGAAGTACGACGTTATTGTTGGCATTAATGGTAAAAAGGTCAGCTCACAGGCTGATCTGCGAGAAGAACT
CTACAAGCATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGCAAACCGTCAAGGTTAAATTAA
CACAGAAATTAGCAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Peptidase family M50 (Peptidase_M50)

(221-375)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5M8XCI1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.394

93.668

0.491
  htrA Streptococcus gordonii str. Challis substr. CH1

48.549

100

0.485
  htrA Streptococcus pneumoniae D39

52.924

90.237

0.478
  htrA Streptococcus pneumoniae TIGR4

52.924

90.237

0.478
  htrA Streptococcus pneumoniae R6

52.924

90.237

0.478
  htrA Streptococcus pneumoniae Rx1

52.924

90.237

0.478
  htrA Streptococcus mutans UA159

52.647

89.71

0.472

Multiple sequence alignment