Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DXE58_RS12790 Genome accession   NZ_LT992456
Coordinates   2470058..2470744 (+) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 1_1439     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2465058..2475744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE58_RS12755 yqeH 2465585..2466685 (+) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -
  DXE58_RS12760 aroE 2466699..2467505 (+) 807 WP_000666746.1 shikimate dehydrogenase -
  DXE58_RS12765 yhbY 2467509..2467799 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DXE58_RS12770 nadD 2467802..2468371 (+) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DXE58_RS12775 yqeK 2468361..2468945 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DXE58_RS12780 rsfS 2468946..2469299 (+) 354 WP_001088020.1 ribosome silencing factor -
  DXE58_RS12785 - 2469302..2470018 (+) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  DXE58_RS12790 comEA 2470058..2470744 (+) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  DXE58_RS12795 - 2470836..2471297 (+) 462 WP_000439690.1 ComE operon protein 2 -
  DXE58_RS12800 comEC 2471302..2473503 (+) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DXE58_RS12805 holA 2473560..2474534 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -
  DXE58_RS12810 rpsT 2474579..2474830 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1032990 DXE58_RS12790 WP_001825349.1 2470058..2470744(+) (comEA) [Staphylococcus aureus isolate 1_1439]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1032990 DXE58_RS12790 WP_001825349.1 2470058..2470744(+) (comEA) [Staphylococcus aureus isolate 1_1439]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment