Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB6M97_RS09535 Genome accession   NZ_CP163514
Coordinates   1932454..1933173 (-) Length   239 a.a.
NCBI ID   WP_121835236.1    Uniprot ID   -
Organism   Streptococcus hillyeri strain S23-3001-1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1927454..1938173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M97_RS09515 (AB6M97_09515) - 1927870..1929096 (-) 1227 WP_121835244.1 cysteine desulfurase -
  AB6M97_RS09520 (AB6M97_09520) sufD 1929179..1930441 (-) 1263 WP_121835242.1 Fe-S cluster assembly protein SufD -
  AB6M97_RS09525 (AB6M97_09525) sufC 1930453..1931229 (-) 777 WP_121835240.1 Fe-S cluster assembly ATPase SufC -
  AB6M97_RS09530 (AB6M97_09530) - 1931303..1932454 (-) 1152 WP_121835238.1 glycosyltransferase family 4 protein -
  AB6M97_RS09535 (AB6M97_09535) mecA 1932454..1933173 (-) 720 WP_121835236.1 adaptor protein MecA Regulator
  AB6M97_RS09540 (AB6M97_09540) - 1933797..1933904 (-) 108 WP_121835234.1 putative holin-like toxin -
  AB6M97_RS09545 (AB6M97_09545) - 1934258..1934365 (-) 108 WP_121835234.1 putative holin-like toxin -
  AB6M97_RS09550 (AB6M97_09550) - 1934812..1935663 (-) 852 WP_369350656.1 sortase -
  AB6M97_RS09555 (AB6M97_09555) - 1935650..1936447 (-) 798 WP_369351215.1 class C sortase -
  AB6M97_RS09560 (AB6M97_09560) - 1936531..1937442 (-) 912 WP_369350658.1 class C sortase -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 27927.39 Da        Isoelectric Point: 4.0984

>NTDB_id=1030367 AB6M97_RS09535 WP_121835236.1 1932454..1933173(-) (mecA) [Streptococcus hillyeri strain S23-3001-1]
MEMKQINEITLKITISMEDLEERGMELHDFLIPQEKTEEFFYSVMDELELPDNFKQSGMLSFRVTPRKDRLDVFVTKSEI
NQDLNFDDLAELGDVSQMSPEDFFKTLEQKMFEKGDVAAHKQLADIEEQEEKSATEEVEETQDYVHYVLDFPTFEEVVTF
CQSIDFPTEASELYKADGRYYMTVLVSLENQPAYYSNIVFARLIEHAHKADRTRAYLQEHGIQLMMDDALPLLRSIEVA

Nucleotide


Download         Length: 720 bp        

>NTDB_id=1030367 AB6M97_RS09535 WP_121835236.1 1932454..1933173(-) (mecA) [Streptococcus hillyeri strain S23-3001-1]
ATGGAAATGAAACAAATCAACGAAATAACGTTGAAAATTACGATCAGTATGGAGGATTTGGAAGAGCGTGGGATGGAACT
ACATGACTTCTTAATTCCTCAAGAAAAAACGGAAGAATTTTTCTATTCTGTTATGGATGAGTTGGAATTACCTGATAATT
TCAAGCAAAGTGGTATGCTTAGTTTTCGTGTGACGCCTCGAAAAGATCGTTTAGATGTCTTTGTGACAAAATCTGAGATT
AATCAAGATTTGAATTTTGACGATTTGGCTGAGCTTGGAGATGTTTCACAGATGTCTCCGGAAGATTTTTTCAAAACGTT
GGAACAAAAGATGTTTGAAAAAGGTGATGTGGCGGCTCATAAACAGTTGGCTGATATTGAAGAACAGGAAGAAAAGAGTG
CAACTGAGGAGGTTGAAGAGACTCAGGATTATGTTCACTATGTTTTGGATTTTCCAACTTTTGAAGAAGTGGTGACGTTT
TGCCAATCAATTGATTTTCCGACAGAGGCTTCAGAGCTTTATAAGGCTGATGGACGTTACTACATGACAGTCTTAGTTTC
TCTTGAAAATCAACCGGCGTACTATTCTAATATTGTTTTTGCACGCTTGATTGAGCATGCTCATAAGGCAGATAGAACGC
GAGCTTATTTACAAGAGCATGGTATTCAACTAATGATGGATGATGCTCTGCCTTTGCTTAGGAGTATCGAGGTGGCTTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.017

100

0.64
  mecA Streptococcus thermophilus LMD-9

57.831

100

0.603
  mecA Streptococcus thermophilus LMG 18311

57.831

100

0.603
  mecA Streptococcus pneumoniae Rx1

49.18

100

0.502
  mecA Streptococcus pneumoniae D39

49.18

100

0.502
  mecA Streptococcus pneumoniae R6

49.18

100

0.502
  mecA Streptococcus pneumoniae TIGR4

49.18

100

0.502

Multiple sequence alignment